Increasing objectivity in quantitative analysis in immune-histochemistry biomarker mapping using upconverting nanoparticles

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dc.contributor.authorMickert, Matthiasen
dc.contributor.authorHelgstrand, Magnusen
dc.contributor.authorKonugolu Venkata Sekar, Sanathanaen
dc.contributor.authorMa, Huien
dc.contributor.authorKomolibus, Katarzynaen
dc.contributor.authorKho, Kiang Weien
dc.contributor.authorJohansson, Andreasen
dc.contributor.authorWallenborg, Sannaen
dc.contributor.authorAndersson-Engels, Stefanen
dc.contributor.funderResearch Irelanden
dc.date.accessioned2025-08-21T11:47:57Z
dc.date.available2025-08-21T11:47:57Z
dc.date.issued2025-04en
dc.description.abstractToday immunohistochemistry (IHC) stains molecular biomarkers for treatment stratification. IHC can become increasingly objective by improving sensitivity, quantification and multiplexing capabilities. We use upconverting nanoparticles to achieve this, potentially leading to improved treatment outcomes.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleidOTu1E.2en
dc.identifier.citationMickert, M., Helgstrand, M., Sekar, S. K. V., Ma, H., Komolibus, K., Kho, K. W., Johansson, A., Wallenborg, S. and Andersson-Engels, S. (2025) 'Increasing objectivity in quantitative analysis in immune-histochemistry biomarker mapping using upconverting nanoparticles', Optica Biophotonics Congress 2025, Technical Digest Series, paper OTu1E.2 (2pp). https://doi.org/10.1364/OMP.2025.OTu1E.2en
dc.identifier.doi10.1364/omp.2025.otu1e.2en
dc.identifier.endpage2en
dc.identifier.isbn978-1-957171-46-3en
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/17798
dc.language.isoenen
dc.publisherOptica Publishing Groupen
dc.relation.ispartofOptica Biophotonics Congress 2025en
dc.relation.ispartofOptical Molecular Probes, Imaging and Drug Delivery 2025, Coronado, CA, United States, 21–24 April 2025en
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Research Professorship Programme/15/RP/2828/IE/Novel applications and techniques for in vivo optical imaging and spectroscopy/en
dc.rights© 2025, the Authors. Published by Optica Publishing Group.en
dc.subjectImmunohistochemistry (IHC)en
dc.subjectUpconverting nanoparticlesen
dc.titleIncreasing objectivity in quantitative analysis in immune-histochemistry biomarker mapping using upconverting nanoparticlesen
dc.typeConference itemen
dc.typeproceedings-articleen
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