2026-09-24T04:15:14Zhttps://cora.ucc.ie/server/oai/requestoai:cora.ucc.ie:10468/180182026-02-23T11:42:56Zcom_10468_289com_10468_6com_10468_67com_10468_5com_10468_388com_10468_1col_10468_290col_10468_805col_10468_389col_10468_8983
we wish to redact the entire thesis. no part of the thesis should be made available.
9999-12-31
Fleming, John V (Eoin)
Algoufi, Noor Daifallah
Ministry of Education - Kingdom of Saudi Arabia
University College Cork
2025-10-10T15:31:33Z
2025-10-10T15:31:33Z
2025
2025
Ube2J1 is an enzyme that helps cells degrade misfolded proteins at the endoplasmic reticulum. This study shows it is controlled by several signalling pathways, and regulated by previously unidentified mechanisms. Ube2J1 also boosts replication of Vesicular Stomatitis Virus when active. These findings reveal wider roles in stress responses, immunity, and disease.
Not peer reviewed
Accepted Version
application/pdf
Algoufi, N. D. 2025. Novel insights into the post-translational regulation of an ER localised ubiquitin conjugating enzyme. PhD Thesis, University College Cork.
221
https://hdl.handle.net/10468/18018
en
University College Cork
University College Cork (School of Pharmacy, School of Biochemistry and Cell Biology)
© 2025, Noor Algoufi.
ER stress
Novel insights into the post-translational regulation of an ER localised ubiquitin conjugating enzyme
Doctoral thesis
Doctoral
PhD - Doctor of Philosophyinfo:eu-repo/semantics/embargoedAccess