Breast cancer is the most common cancer in women globally, with incidence rates increasing and survival rates varying widely depending on early detection and access to treatment. In Ireland, the number of diagnoses is ...

The process of gene expression was long believed to be fixed across all domains of life, set in stone by both the universality of the genetic code and the protein-synthesising machinery that decodes it. However, exceptions ...

The evolutionarily conserved Insulin-Like Growth Factor 1 (IGF-1) signalling pathway is essential for growth and development and may facilitate cancer progression. While IGF-1 mediates mitochondria protection in some ...

Insulin-like Growth Factor-1 Receptor signalling is essential for cell growth, and also promotes migration, survival and cellular transformation, thus, linking it to cancer progression. IGF-1R activity and signalling in ...

Background: Colorectal cancer (CRC) has a complex aetiology involving both genetic and environmental factors. Recently, attention has turned to the influence of the gut microbiota upon the development of CRC. The human gut ...