Highly stable PEGylated gold nanoparticles in water: applications in biology and catalysis
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Date
2012-08
Authors
Rahme, Kamil
Nolan, Marie-Therese
Doody, Timothy
McGlacken, Gerard P.
O'Driscoll, Caitríona M.
Holmes, Justin D.
Journal Title
Journal ISSN
Volume Title
Publisher
NSTI-Nanotech
Published Version
Abstract
Gold nanoparticles (Au NPs) with diameters ranging between 5-60 nm have been synthesised in water, and further stabilized with polyethylene glycol-based thiol polymers (mPEG-SH). Successful PEGylation of the Au NPs was confirmed by Dynamic Light scattering (DLS) and Zeta potential measurements. PEG coating of the Au NPs is the key of their colloidal stabilty, and its successful applications. Catalytic efficiency testing of the PEG-AuNPs were carried out on homocoupling of boronic acid. PEG-Au NPs with AuNps diameter < 30 nm were useful as catalyst in water. Finally, the PEG-Au NPs were also shown to be stable in biological fluid and not cytotoxic on B16.F10 cell line, making them attractive for further studies.
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Keywords
Gold nanoparticles , Stabilisation , Polyethylene glycol , PEG , Ullmann reaction , Cytotoxicity , Ge , Nanowires , Transmission electron microscopy
Citation
Rahme, K.; Nolan. M. T.; Doody, T.; McGlacken, P.; O Driscoll, C.; Holmes, J. D. (2012) ‘Highly stable PEGylated gold nanoparticles in water: applications in biology and catalysis’. Nanotech 2012. 18-21 June. Santa Clara, CA. In: Nanotech 2012, vol. 1. pp 5-8. ISBN:978-1-4665-6274-5
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Copyright
© 2012 Nano Science and Technology Institute.