• Synthesis of novel quorum sensing inhibitors of DSF 

  Horgan, Conor (University College Cork, 2022)

  Antimicrobial resistance (AMR) has become a growing concern among the medical community with many previously effective antibiotics losing their efficacy. Much of this AMR is thought to stem from biofilm formation controlled ...
• Studies in derivatisation and direct arylation of heterocycles 

  Hickey, Aobha (University College Cork, 2022)

  Quorum sensing (QS) is a complex form of communication employed by bacterial species to coordinate group behaviours through the biosynthesis, secretion and detection of small molecules known as autoinducers (AIs). Understanding ...
• Applications of Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS) in pharmaceutical analysis 

  O'Mahoney, Niamh (University College Cork, 2022-02-08)

  Dissolution testing is one of the most time-consuming, costly, and laborious tasks in the pharmaceutical industry, and yet it is a cornerstone of quality control testing and product release. Dissolution testing is a ...
• Studies in the synthesis and analysis of novel heterocyclic synthetic cannabinoid receptor agonists 

  Alam, Ryan (University College Cork, 2022-03-08)

  Over the past decade, synthetic cannabinoid receptor agonists (SCRA) have come to represent a diverse category of new psychoactive substance (NPS). However, from a chemical perspective, little is known about the ...
• Hydrophilic interaction liquid chromatography for biologically important metal complex speciation and low molecular weight ligand analysis 

  Alsaeedi, Majidah (University College Cork, 2022-07-14)

  Metal ions play crucial roles both from a biological and an environmental perspective. They circulate around the human body by coordinating with selected biological molecules to generate stable and strong bonding to reach ...

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