• Greener methodology for the synthesis of alpha-diazocarbonyl compounds and a novel approach to dioxinone derivatives 

  O'Brien, Claire (University College Cork, 2016)

  This thesis outlines a more environmentally benign approach to diazo transfer, and the investigation of the reactivity of -diazocarbonyl compounds when subjected to transition metal and lanthanide catalysis. Extensive ...
• Chemoenzymatic routes to enantiopure hydroxytetrahydrofurans: muscarine and its analogues 

  Beecher, Denis (University College Cork, 2015)

  Muscarine was identified as an active principle of the poisonous mushroom Amanita muscaria over 170 years ago and has been identified as an agonist of acetylcholine. The synthesis of all stereoisomers of muscarine have ...
• Access to modified geiparvarins using Pd(0)-mediated C-C bond forming reactions 

  Lynch, Denis (University College Cork, 2014)

  Geiparvarin is a natural product which contains both a 3(2H)-furanone and a coumarin moiety in its structure. The aim of this project was to investigate the use of Pd(0)-mediated C–C bondforming reactions to produce ...
• Crystallisation and crystal forms of carbohydrate derivatives 

  Lennon, Lorna (University College Cork, 2014)

  This thesis is focused on the synthesis and solid state analysis of carbohydrate derivatives, including many novel compounds. Although the synthetic chemistry surrounding carbohydrates is well established in the literature, ...
• Copper-catalysed asymmetric sulfide oxidation 

  O'Mahony, Graham E. (University College Cork, 2013)

  The focus of this thesis is the preparation of enantiopure sulfoxides by means of copper-catalysed asymmetric sulfoxidation, with particular emphasis on the synthesis of aryl benzyl and aryl alkyl sulfoxides. Chapter 1 ...

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