• Novel rhodium carboxylates as powerful enantioselective catalysts 

  Buckley, Aoife (University College Cork, 2019)

  This thesis describes the design and synthesis of novel rhodium carboxylates for use as enantioselective catalysts in transformations of α-diazocarbonyl compounds. Enantioselectivities of up to 93% ee were achieved in a ...
• Crystallisation kinetics of organic compounds; quinacridone derivatives as UV-active probes of solution state pre-nucleation phenomena 

  Shanahan, Louise (University College Cork, 2019)

  An ideal crystallisation process is predictable and reproducible; a less than simple ask. The influence of pre-nucleation molecular interactions in solution on the crystallised phase obtained has been highlighted. To improve ...
• New biosensors for metabolic imaging 

  O'Donnell, Neil (University College Cork, 2018)

  Tissue engineering is a multi-disciplinary field that involves three-dimensional cell and tissue models, live cell microscopy and related imaging modalities, along with fluorescence and phosphorescence-based biosensors. ...
• Ellipticine derivatives: targeting cell proliferation by a structured approach 

  McKee, Mary (University College Cork, 2019)

  Ellipticine and its derivatives are molecules which possess potent anticancer activity. This thesis explores the synthesis of novel ellipticine derivatives, as well as modifications of the template, and evaluates their ...
• Applications development of broadband acoustic resonance dissolution spectroscopy (BARDS) in the pharmaceutical, food and animal nutrition industries 

  Ahmed, M. Rizwan (University College Cork, 2018)

  Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS) is a novel analytical tool for the characterisation of powders, blends, tablets and a myriad of formulations. It is based on a phenomenon which occurs during ...

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