• Ellipticine derivatives: targeting cell proliferation by a structured approach 

  McKee, Mary (University College Cork, 2019)

  Ellipticine and its derivatives are molecules which possess potent anticancer activity. This thesis explores the synthesis of novel ellipticine derivatives, as well as modifications of the template, and evaluates their ...
• Applications development of broadband acoustic resonance dissolution spectroscopy (BARDS) in the pharmaceutical, food and animal nutrition industries 

  Ahmed, Mohammed Rizwan (University College Cork, 2018)

  Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS) is a novel analytical tool for the characterisation of powders, blends, tablets and a myriad of formulations. It is based on a phenomenon which occurs during ...
• Design and synthesis of novel sulfur-containing antiviral analogues 

  Jones, David J. (University College Cork, 2018)

  Chapter One of this thesis presents a consolidated review of methods for the formation of phosphorus-sulfur bonds. This review focuses on the synthesis of phosphorothioates, phosphonothioates, phosphinothioates and ...
• Studying sequence effects of mRNA 5' cap juxtapositions on translation initiation rate using randomization strategy of the extreme 5' end of mRNA 

  Pai, Anjali (University College Cork, 2018)

  Translation initiation is a complex process. The efficiency of translation initiation is determined not just by activity and availability of the translation initiation apparatus, but also the properties of mRNA 5’transcript ...
• Biocatalysis in organic synthesis 

  Foley, Aoife M. (University College Cork, 2019)

  The first chapter provides an overview of the use of biocatalysis for the synthesis of pharmaceutical intermediates and natural products. This review focuses, in particular, on the impact of recent developments in technologies ...

View more