• ‘It’s a nice thing to do but…’: exploring the methods and impact of patient and public involvement (PPI) in trials 

  Racine, Emmy (University College Cork, 2020-10-02)

  Background and Aims: Patient and Public Involvement (PPI), defined as research carried out ‘with’ or ‘by’ members of the public rather than ‘to’, ‘about’ or ‘for’ them, is increasingly recognized as an essential component ...
• The effects of stressors during early life on hippocampal neurogenesis and microglial activation in the male and female brain 

  McGovern, Andrew Joseph (University College Cork, 2021-04-05)

  Stress during critical periods of brain development and maturation such as adolescence is associated with an increased risk of developing stress-related psychiatric disorders which are more common in women than men. Early ...
• Exploring the utility of lipid-based formulation technology to enhance oral bioavailability of BCS class IV molecules 

  Köhl, Niklas J. (University College Cork, 2020-04-30)

  Purpose: Increasing numbers of poorly water-soluble drugs emerging from discovery pipelines have led to formulation delivery challenges. Poorly water-soluble drugs that exhibit limited in vivo bioavailability generate a ...
• Experiences of pregnancy with major fetal anomalies 

  Power Walsh, Stacey (University College Cork, 2020-09-24)

  Background: Two to three percent of pregnancies will receive a diagnosis of a congenital anomaly, of which a proportion are fatal. While the prevalence of congenital anomalies is low it is the leading cause of fetal death ...
• Macrophage polarisation: the impact of M1 versus M2 polarisation on host innate immune responses to bacterial infection 

  Foley, Niamh M. (University College Cork, 2015-12)

  Background and Aim: Infection is a global burden causing millions of deaths per annum worldwide. In the US sepsis is the tenth leading cause of death with the mortality associated with severe sepsis estimated at 30-50%. ...

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