• The role of regulatory T cells in stroke recovery 

  Malone, Kyle (University College Cork, 2022-06-16)

  Background: Acute ischaemic stroke is a major cause of mortality worldwide. Despite the search for new therapies, tissue plasminogen activator remains the only FDA-approved medication. The immune system is involved in all ...
• Phenotyping for a personalised approach to CVD prevention 

  McEvoy, John William (University College Cork, 2022-03-01)

  Cardiovascular disease (CVD) prevention requires interventions at the level of the population (public health) and at the level of individuals (medical care). Therapeutic options to reduce the risk of CVD among at risk ...
• Novel insights into early life stress-induced dysfunction of the gut-brain axis 

  Collins, James M. (University College Cork, 2022-05-27)

  Visceral pain, a debilitating hallmark of disorders of gut-brain axis interactions such as irritable bowel syndrome, has a major impact on quality of life. Given the increasing prevalence of irritable bowel syndrome over ...
• Characterisation of the molecular mechanisms of dopaminergic axonal growth and their impairment in Parkinson's disease 

  Anantha, Jayanth (University College Cork, 2021)

  Parkinson’s disease (PD) is a neurodegenerative disease that affects 6.1 million people globally as of 2016. Axonal degeneration has been identified as the earliest event in the pathogenesis of the disease. For this reason, ...
• Investigations on the role of the gut microbiota in hippocampal neuroplasticity and behaviour throughout the lifespan 

  Guzzetta, Katherine E. (University College Cork, 2022-02-11)

  Trillions of microorganisms inhabit the gastrointestinal tract, and while their importance in host digestion is well established, these microbes have recently been shown to harness the ability to influence neuroplasticity ...

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