• Pharmacological optimisation of ultrasound guided axillary brachial plexus block 

  Malladihalli Ranganath, Anil Kumar (University College Cork, 2021-07)

  Regional anaesthesia provide significant advantages in the perioperative care of the patient undergoing surgery, including improved postoperative analgesia, a reduction in adverse events, shorter recovery time, and expedited ...
• A mixed methods study of the relationship between organisational readiness to change, service user engagement and innovation adoption in community-based opiate substitute treatment services in Ireland 

  Kelly, Peter (University College Cork, 2021-06)

  Introduction: While we know that treatment for opiate dependence, such as opiate substitution therapy and psychosocial interventions delivered in community settings are effective, we do not know exactly why they are ...
• An investigation on proteolysis of the ACE2 receptor and its involvement in the cellular uptake and transmission of SARS-CoV-2 

  Wakerlin, Samantha Leigh (University College Cork, 2021-12-21)

  The renin-angiotensin system (RAS) is a key physiologic signalling network in blood and tissue homeostasis in humans. Angiotensin-converting enzyme 2 (ACE2) is a key regulator of the protective axis in RAS signalling as ...
• Defining the potential of class-IIa histone deacetylases as a therapeutic target for Parkinson’s disease 

  Mazzocchi, Martina (University College Cork, 2021-11-15)

  Parkinson’s disease (PD) is a neurodegenerative disease characterized by early dopaminergic (DA) neuron degeneration, coupled with intracellular aggregation of α-synuclein (α-syn) in Lewy Bodies (LB). Given the lack of a ...
• Surguvant inflammation and metabolism in colorectal surgery 

  Fleming, Christina A. (University College Cork, 2020)

  Background: It is believed that dysregulated perioperative inflammation (POI) and altered cellular and systemic metabolism in the perioperative period may predispose to colon cancer recurrence. This thesis examined the ...

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