A scalable optoelectronic neural probe architecture with self-diagnostic capability

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Zhao, Hubin
Soltan, Ahmed
Maaskant, Pleun P.
Dong, Na
Sun, Xiaohan
Degenaar, Patrick
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Institute of Electrical and Electronics Engineers (IEEE)
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There is a growing demand for the development of new types of implantable optoelectronics to support both basic neuroscience and optogenetic treatments for neurological disorders. Target specification requirements include multi-site optical stimulation, programmable radiance profile, safe operation, and miniaturization. It is also preferable to have a simple serial interface rather than large numbers of control lines. This paper demonstrates an optrode structure comprising of a standard complementary metal-oxide-semiconductor process with 18 optical stimulation drivers. Furthermore, diagnostic sensing circuitry is incorporated to determine the long-term functionality of the photonic elements. A digital control system is incorporated to allow independent multisite control and serial communication with external control units.
Light emitting diodes , Optical pulses , Optical sensors , Probes , Shafts , Stimulated emission , Active optrode , Implantable , Neural stimulation , Optogenetics , Self-diagnostic.
Zhao, H., Soltan, A., Maaskant, P., Dong, N., Sun, X. and Degenaar, P. (2018) 'A Scalable Optoelectronic Neural Probe Architecture With Self-Diagnostic Capability', IEEE Transactions on Circuits and Systems I: Regular Papers, 65(8), pp.2431-2442. doi: 10.1109/TCSI.2018.2792219
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