• Evidence for dopaminergic axonal degeneration as an early pathological process in Parkinson's disease 

  O'Keeffe, Gerard W.; Sullivan, Aideen M. (Elsevier Ltd., 2018-06-19)

  Parkinson's disease is a common neurodegenerative disorder presenting with a variety of motor and non-motor symptoms. The motor symptoms manifest as a result of the progressive degeneration of midbrain dopaminergic neurons. ...
• Intervention strategies for cesarean section-induced alterations in the microbiota-gut-brain axis 

  Moya-Pérez, Angela; Luczynski, Pauline; Renes, Ingrid B.; Wang, Shugui; Borre, Yuliya; Ryan, C. Anthony; Knol, Jan; Stanton, Catherine; Dinan, Timothy G.; Cryan, John F. (Oxford University Press, 2017)

  Microbial colonization of the gastrointestinal tract is an essential process that modulates host physiology and immunity. Recently, researchers have begun to understand how and when these microorganisms colonize the gut ...
• The microbiome regulates amygdala-dependent fear recall 

  Hoban, Alan E.; Stilling, Roman M.; Moloney, Gerard; Shanahan, Fergus; Dinan, Timothy G.; Clarke, Gerard; Cryan, John F. (Nature Publishing Group, 2018)

  The amygdala is a key brain region that is critically involved in the processing and expression of anxiety and fear-related signals. In parallel, a growing number of preclinical and human studies have implicated the ...
• Poor cognitive ageing: vulnerabilities, mechanisms and the impact of nutritional interventions 

  Miguel, Sophie; Champ, Claire; Day, Jon; Aarts, Esther; Bahr, Ben A.; Bakker, Martijntje; Bánáti, Diana; Calabrese, Vittorio; Cederholm, Tommy; Cryan, John; Dye, Louise; Farrimond, Jonathan A.; Korosi, Aniko; Layé, Sophie; Maudsley, Stuart; Milenkovic, Dragan; Mohajeri, M. Hasan; Sijben, John; Solomon, Alina; Spencer, Jeremy P. E.; Thuret, Sandrine; Vanden Berghe, Wim; Vauzour, David; Vellas, Bruno; Wesnes, Keith; Willatts, Peter; Wittenberg, Raphael; Geurts, Lucie (Elsevier Ltd, 2018)

  Background: Ageing is a highly complex process marked by a temporal cascade of events, which promote alterations in the normal functioning of an individual organism. The triggers of normal brain ageing are not well understood, ...
• Acute in utero exposure to lipopolysaccharide induces inflammation in the pre- and postnatal brain and alters the glial cytoarchitecture in the developing amygdala 

  O'Loughlin, Elaine; Pakan, Janelle M. P.; Yilmazer-Hanke, Deniz; McDermott, Kieran W. (BioMed Central Ltd., 2017)

  Background: Maternal immune activation (MIA) is a risk factor for neurodevelopmental disorders such as autism and schizophrenia, as well as seizure development. The amygdala is a brain region involved in the regulation of ...

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