• Preclinical evaluation of a novel AAV-GDF5 vector in a 6-OHDA model of Parkinson’s disease and evaluation of the effect of 6-OHDA on the expression of HDACs 

  Shanahan, Sarah Elizabeth (University College Cork, 2020-08-17)

  Neurotrophic factors have shown promising results as potential disease-altering treatment methods for Parkinson’s disease (PD). However, there are many risks associated with surgically accessing such deeply located regions ...
• The microbiota-gut-brain axis 

  Cryan, John F.; O'Riordan, Kenneth J.; Cowan, Caitlin S. M.; Sandhu, Kiran V.; Bastiaanssen, Thomaz F. S.; Boehme, Mcusra; Codagnone, Martin G.; Cussotto, Sofia; Fulling, Christine; Golubeva, Anna V.; Guzzetta, Katherine E.; Jaggar, Minal; Long-Smith, Caitriona M. .; Lyte, Joshua M.; Martin, Jason A.; Molinero-Perez, Alicia; Moloney, Gerard; Morelli, Emanuela; Morillas, Enrique; O'Connor, Rory; Cruz-Pereira, Joana S.; Peterson, Veronica L.; Rea, Kieran; Ritz, Nathaniel L.; Sherwin, Eoin; Spichak, Simon; Teichman, Emily M.; van de Wouw, Marcel; Ventura-Silva, Ana Paula; Wallace-Fitzsimons, Shauna E.; Hyland, Niall; Clarke, Gerard; Dinan, Timothy G. (American Physiological Society, 2019-08-28)

  The importance of the gut-brain axis in maintaining homeostasis has long been appreciated. However, the past 15 yr have seen the emergence of the microbiota (the trillions of microorganisms within and on our bodies) as one ...
• Enduring effects of an unhealthy diet during adolescence on systemic but not neurobehavioural measures in adult rats 

  Nicolas, Sarah; Ó Léime, Ciarán S.; Hoban, Alan E.; Hueston, Cara M.; Cryan, John F.; Nolan, Yvonne M. (Taylor & Francis Group, 2020-07-29)

  Introduction: Adolescence is an important stage of maturation for various brain structures. It is during this time therefore that the brain may be more vulnerable to environmental factors such as diet that may influence ...
• The universal design for learning framework in anatomical sciences education 

  Balta, Joy Y.; Supple, Briony; O'Keeffe Gerard W. (John Wiley & Sons, Inc., 2020-06-15)

  Over the past decades, teaching and learning within the discipline of anatomy has undergone significant changes. Some of these changes are due to a reduction in the number of teaching hours, while others are related to ...
• The role of the gut microbiome in the development of schizophrenia 

  Kelly, John R.; Minuto, Chiara; Cryan, John F.; Clarke, Gerard; Dinan, Timothy G. (Elsevier, 2020-04-23)

  Schizophrenia is a heterogeneous neurodevelopmental disorder involving the convergence of a complex and dynamic bidirectional interaction of genetic expression and the accumulation of prenatal and postnatal environmental ...

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