• Investigations into the role of microbiota-gut-brain axis on behaviour and physiology in the mouse 

  O'Connor, Rory (University College Cork, 2019-12-16)

  The growing recognition of the influence of the intestinal microbiota over the brain and behaviour has led to a shift in the world of neuroscience. Recent developments in the understanding of the microbiota-gut-brain axis ...
• Novel insights into the mechanisms underlying the anti-obesity effects of whey protein 

  Boscaini, Serena (University College Cork, 2020-09-25)

  Obesity has become one of the major health problems worldwide, due to modern eating habits and an increase in sedentary lifestyles. Dietary strategies represent one among different therapeutic approaches employed to ...
• Diet and depression: exploring the biological mechanisms of action 

  Marx, Wolfgang; Lane, Melissa; Hockey, Meghan; Aslam, Hajara; Berk, Michael; Walder, Ken; Borsini, Alessandra; Firth, Joseph; Pariante, Carmine M.; Berding, Kirsten; Cryan, John F.; Clarke, Gerard; Craig, Jeffrey M.; Su, Kuan-Pin; Mischoulon, David; Gomez-Pinilla, Fernando; Foster, Jane A; Cani, Patrice D.; Thuret, Sandrine; Staudacher, Heidi M.; Sánchez-Villegas, Almudena; Arshad, Husnain; Akbaraly, Tasnime; O'Neil, Adrienne; Segasby, Toby; Jacka, Felice N. (Springer Nature Limited, 2020-11-03)

  The field of nutritional psychiatry has generated observational and efficacy data supporting a role for healthy dietary patterns in depression onset and symptom management. To guide future clinical trials and targeted ...
• Strain differences in behaviour and immunity in aged mice: Relevance to autism. 

  O'Connor, Rory; Van De Wouw, Marcel; Moloney, Gerard M.; Ventura-Silva, Ana Paula; O'Riordan, Ken; Golubeva, Anna; Dinan, Timothy G.; Schellekens, Harriët; Cryan, John F. (Elsevier B.V., 2020-11-20)

  The BTBR mouse model has been shown to be associated with deficits social interaction and a pronounced engagement in repetitive behaviours. Autism spectrum disorder (ASD) is the most prevalent neurodevelopmental condition ...
• Preclinical evaluation of a novel AAV-GDF5 vector in a 6-OHDA model of Parkinson’s disease and evaluation of the effect of 6-OHDA on the expression of HDACs 

  Shanahan, Sarah Elizabeth (University College Cork, 2020-08-17)

  Neurotrophic factors have shown promising results as potential disease-altering treatment methods for Parkinson’s disease (PD). However, there are many risks associated with surgically accessing such deeply located regions ...

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