• The gut microbiome influences the bioavailability of olanzapine in rats. 

  Cussotto, Sofia; Walsh, Jacinta; Golubeva, Anna V.; Zhdanov, Alexander V.; Strain, Conall R.; Fouhy, Fiona; Stanton, Catherine; Dinan, Timothy G.; Hyland, Niall P.; Clarke, Gerard; Cryan, John F.; Griffin, Brendan T. (Elsevier, 2021-04-02)

  Background: The role of the gut microbiome in the biotransformation of drugs has recently come under scrutiny. It remains unclear whether the gut microbiome directly influences the extent of drug absorbed after oral ...
• The role of retinoic acid in glioma growth control 

  Flynn, Patricia Margaret (University College Cork, 2021-07-22)

  Tumours of the central nervous system are known as gliomas, arising from the astrocytes, oligodendrocytes, ependymal cells or from glial progenitor cells. Although a relatively rare diagnosis, there is disproportionate ...
• Deciphering the role of microbially-derived metabolites on the microbiota-gut-brain axis 

  Spichak, Simon (University College Cork, 2021-01-25)

  The trillions of microbial organisms residing in the gut, microbiota, are now recognized as major modulators of physiology and health, quickly becoming one of the most exciting emerging areas in neuroscience. Preclinical ...
• Mining the microbiome for markers of microbiota-gut brain communication and mental health 

  Bastiaanssen, Thomaz F. S. (University College Cork, 2021-03-29)

  There has been a growing acknowledgement of the involvement of the gut microbiome - the collection of microbes that reside in our gut - in regulating our mood and behaviour. This phenomenon is referred to as the ...
• Psychobiotics: Evolution of novel antidepressants 

  Dinan, Timothy G.; Butler, Mary I.; Cryan, John F. (S. Karger AG, Basel, 2021)

  The gut-brain axis is a bidirectional communication system which allows the central nervous system and gastrointestinal tract to interact with and respond to each other rapidly and effectively. It is becoming increasingly ...

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