• The association between preeclampsia and childhood development and behavioural outcomes 

  Maher, Gillian M.; O'Keeffe, Gerard W.; O'Keeffe, Linda M.; Matvienko-Sikar, Karen; Dalman, Christina; Kearney, Patricia M.; McCarthy, Fergus P.; Khashan, Ali S. (Springer Nature Switzerland AG, 2020-04-11)

  Objectives: To examine the associations between preeclampsia and longitudinal child developmental and behavioural outcomes using data from a nationally representative study of children living in Ireland. Methods: We used ...
• From neurons to neuroblastoma: dietary flavonoids as regulators of life, death & differentiation 

  Alshangiti, Amnah M. (University College Cork, 2020-03-24)

  Neuroblastoma (NB) is an embryonal malignancy that arises from cells of sympathoadrenal lineage during the development of the nervous system. Patients classified as stage 4 with aggressive tumors are considered to belong ...
• Gut microbiome-mediated modulation of hepatic cytochrome P450 and P-glycoprotein: impact of butyrate and fructo-oligosaccharide-inulin 

  Walsh, Jacinta; Gheorghe, Cassandra E.; Lyte, Joshua M.; van de Wouw, Marcel; Boehme, Marcus; Dinan, Timothy G.; Cryan, John F.; Griffin, Brendan T.; Clarke, Gerard; Hyland, Niall P. (Wiley, 2020-04-26)

  Objectives: Our objective was to demonstrate microbial regulation of hepatic genes implicated in drug metabolism and transport using germ‐free (GF) mice and to explore the impact of a microbial metabolite, butyrate, and a ...
• Polyphenols selectively reverse early-life stress-induced behavioural, neurochemical and microbiota changes in the rat 

  Donoso, Francisco; Egerton, Sian; Bastiaanssen, Thomaz F. S.; Fitzgerald, Patrick; Gite, Snehal; Fouhy, Fiona; Ross, R. Paul; Stanton, Catherine; Dinan, Timothy G.; Cryan, John F. (Elsevier Ltd., 2020-04-10)

  There is a growing emphasis on the role of the microbiota-gut-brain axis as modulator of host behaviour and as therapeutic target for neuropsychiatric disorders. In addition, accumulating evidence suggests that early-life ...
• When rhythms meet the blues: Circadian interactions with the microbiota-gut-brain axis 

  Teichman, Emily M.; O'Riordan, Kenneth J.; Gahan, Cormac G. M.; Dinan, Timothy G.; Cryan, John F. (Elsevier Inc., 2020-03-03)

  The microbiota-gut-brain axis encompasses a bidirectional mode of communication between the microorganisms residing in our gut, and our brain function and behavior. The composition of the gut microbiota is subject to diurnal ...

View more