• Exploring the utility of lipid-based formulation technology to enhance oral bioavailability of BCS class IV molecules 

  Köhl, Niklas J. (University College Cork, 2020-04-30)

  Purpose: Increasing numbers of poorly water-soluble drugs emerging from discovery pipelines have led to formulation delivery challenges. Poorly water-soluble drugs that exhibit limited in vivo bioavailability generate a ...
• Exploring the utility of the pig model for predicting bioavailability in humans 

  Henze, Laura J. (University College Cork, 2020-07-01)

  Purpose It has been increasingly recognised that there is a need to reduce costly drug development delays and facilitate earlier access to market for new medicines. Within drug development, there is considerable debate on ...
• Application of pharmaceutical quality approaches and the development of process analytical technologies to improve pharmaceutical product and process understanding 

  Queiroz, Ana Luiza P. (University College Cork, 2020-09-29)

  The pharmaceutical industry is undergoing a paradigm change with the advancement towards the Fourth Industrial Revolution. The manufacturing framework is moving from batch to continuous, which has been accompanied by the ...
• Patient safety culture in Irish healthcare: a mixed-methods investigation 

  Gleeson, Laura (University College Cork, 2020-10)

  Introduction: Medical error is a leading cause of preventable harm worldwide. Patient safety culture has been described as the way in which members of a healthcare organisation think about and prioritise safety. The patient ...
• Using the health policy triangle framework to describe local, regional and national healthcare policy changes within Ireland's diverse healthcare settings 

  O'Brien, Gary L. (University College Cork, 2020)

  Introduction: Developed in the late 20th century, the conceptual descriptive framework for this thesis was inspired by Walt and Gilson’s health policy triangle (HPT). The HPT model is a policy analysis framework universally ...

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