• Rationalising antipsychotic prescribing in dementia: a mixed-methods investigation 

  Walsh, Kieran (University College Cork, 2019)

  Introduction: Antipsychotics are commonly prescribed to people with dementia, especially in nursing homes, despite limited benefits and significant harms. There have been calls to better understand the reasons why ...
• Mechanistic understanding of bioenabling formulation approaches to improve oral bioavailability using porcine in vivo and in silico models 

  O'Shea, Joseph P. (University College Cork, 2018)

  Objectives: Mesoporous silicas (SLC) have demonstrated considerable potential to improve bioavailability of poorly soluble drugs by facilitating rapid dissolution and generating supersaturation. The addition of certain ...
• The implementation of a family-focused lifestyle programme for managing childhood obesity in the community setting in Ireland 

  Kelleher, Emily Geraldine (University College Cork, 2017)

  Background and aim: Childhood obesity is a significant public health issue. International guidelines continue to recommend family-focused, multicomponent, childhood weight management programmes despite limited evidence on ...
• A study of microcrystalline cellulose variability and how this impacts compaction performance 

  Crowley, Mary Ellen (University College Cork, 2018)

  Quality by Design (QbD) is driving the pharmaceutical industry to better understand the impact of raw material variability on the performance and manufacturability of drug products. Identifying excipients critical material ...
• Pre-clinical development of cyclodextrin-based nanoparticles for oral delivery of protein/peptide drugs-in vitro and in vivo evaluation 

  Presas, Elena (University College Cork, 2018)

  Over the past decades, oral protein delivery has become a major research area for pharmaceutical companies. Ideally, once the protein is orally administered, it should remain stable until it reaches the targeted site of ...

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