• Using the health policy triangle framework to describe local, regional and national healthcare policy changes within Ireland's diverse healthcare settings 

  O'Brien, Gary L. (University College Cork, 2020)

  Introduction: Developed in the late 20th century, the conceptual descriptive framework for this thesis was inspired by Walt and Gilson’s health policy triangle (HPT). The HPT model is a policy analysis framework universally ...
• Scale-up and optimisation of the β-chloroacrylamide process by batch and continuous flow methods 

  Dennehy, Olga C. (University College Cork, 2020-04)

  α-Thio-β-chloroacrylamides are a class of highly versatile synthetic intermediates due to their diverse functionality. The three step synthesis to form these compounds provided a model system to optimise and scale-up a ...
• Lyophilisation of high concentration protein formulations 

  Gervasi, Valeria (University College Cork, 2020)

  Antibodies form the main class of commercial therapeutic proteins and are intended for the treatment of several chronic diseases. The current trend is to formulate antibodies at high concentrations in order to deliver a ...
• Gut microbiome-xenobiotic interactions: focus on drug metabolism 

  Walsh, Jacinta (University College Cork, 2020-03-06)

  The fate and activity of drugs are frequently dictated not only by the host per se but also by the microorganisms present in the gastrointestinal tract. While the ever-increasing scientific breakthroughs have highlighted ...
• Exploring vaccine decision-making to identify and address barriers to vaccine uptake in Ireland 

  Marshall, Sarah (University College Cork, 2020-04-05)

  Introduction: Vaccination is one of the greatest public health achievements of the last century. However, vaccine uptake rates worldwide remain sub-optimal. The vaccine decision-making process is complex and multifaceted ...

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