Convenient and robust one-pot synthesis of symmetrical and unsymmetrical benzyl thioethers from benzyl halides using thiourea

Eccles, Kevin S.; Elcoate, Curtis J.; Lawrence, Simon E.; Maguire, Anita R.

Convenient and robust one-pot synthesis of symmetrical and unsymmetrical benzyl thioethers from benzyl halides using thiourea

Files

KSE_ConvenientPV2010.pdf(224.73 KB)

Published Version

Date

2010-07-07

Authors

Eccles, Kevin S.

Elcoate, Curtis J.

Lawrence, Simon E.

Maguire, Anita R.

Publisher

ARKAT USA

Abstract

A series of symmetrical and unsymmetrical benzyl thioethers have been synthesised using a one-pot reaction from benzyl halides and thiourea. This procedure avoids the isolation or handling of malodorous thiols and generates high yields of benzyl thioethers in excellent purity.

Keywords

Unsymmetrical benzyl thioethers , Symmetrical benzyl thioethers

Citation

K.S. ECCLES, C.J. ELCOATE, S.E. LAWRENCE, AND A.R. MAGUIRE.; 2010. Convenient and robust one-pot synthesis of symmetrical and unsymmetrical benzyl thioethers from benzyl halides using thiourea. Arkivoc, 216-228.