Metal-free heterogeneous and mesoporous biogenic graphene-oxide nanoparticle-catalyzed synthesis of bioactive benzylpyrazolyl coumarin derivatives
Siddiqui, T. A. J.; Ghule, Balaji G.; Shaikh, Shoyebmohamad; Shinde, Pritamkumar V.; Gunturu, Krishna Chaitanya; Zubaidha, P. K.; Yun, Je Moon; O'Dwyer, Colm; Mane, Rajaram S.; Kim, Kwang Ho
Date:
2018-05-14
Copyright:
© The Royal Society of Chemistry 2018. Open Access. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence
Citation:
Siddiqui, T. A. J., Ghule, B. G., Shaikh, S., Shinde, P., Gunturu, K. C., Zubaidha, P. K., Yun, J. M., O'Dwyer, C., Mane, R. S. and Kim, K. H. (2018) 'Metal-free heterogeneous and mesoporous biogenic graphene-oxide nanoparticle-catalyzed synthesis of bioactive benzylpyrazolyl coumarin derivatives', RSC Advances, 8(31), pp. 17373-17379. doi: 10.1039/c7ra12550j
Abstract:
We report the preparation of graphene oxide nanoparticles (GONPs), a metal-free, heterogeneous, non-toxic, reusable and mesoporous green-(acid)-catalyst obtained by sugar carbonization through a micro-wave chemical synthesis method for the synthesis of bio-active benzylpyrazolyl coumarin derivatives (BCDs) under thermal conditions (50 [degree]C) in ethanol solvent. The obtained products were purified by re-crystallization from ethanol, assuring usability of GONPs in multicomponent reactions (MCRs) that could find wide application in the synthesis of a variety of biologically potent molecules of therapeutic significance.
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Except where otherwise noted, this item's license is described as © The Royal Society of Chemistry 2018. Open Access. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence