• Investigation of mechanisms underpinning host-microbial interactions in the gastrointestinal tract 

  Udayan, Sreeram (University College Cork, 2019)

  Research in the areas of microbiome science and immunology have identified different members of a host’s microbiota, particularly bacteria, as having critical roles in shaping the development and function of both intestinal ...
• PDLIM2 is a marker of adhesion and β-catenin activity in triple-negative breast cancer 

  Cox, Orla T.; Edmunds, Shelley J.; Simon-Keller, Katja; Li, Bo; Moran, Bruce; Buckley, Niamh E.; Bustamante- Garrido, Milán F.; Healy, Nollaig; O'Flanagan, Ciara H.; Gallagher, William M.; Kennedy, Richard D.; Bernards, René; Caldas, Carlos; Chin, Suet-Feung; Marx, Alexander; O'Connor, Rosemary (American Association for Cancer Research, 2019-03-18)

  The PDLIM2 protein regulates stability of transcription factors including NF-κB and STATs in epithelial and hemopoietic cells. PDLIM2 is strongly expressed in certain cancer cell lines that exhibit an Epithelial-to-Mesenchymal ...
• New biosensors for metabolic imaging 

  O'Donnell, Neil (University College Cork, 2018)

  Tissue engineering is a multi-disciplinary field that involves three-dimensional cell and tissue models, live cell microscopy and related imaging modalities, along with fluorescence and phosphorescence-based biosensors. ...
• Biochemical and biomolecular effects induced by a static magnetic field in Saccharomyces cerevisiae: evidence for oxidative stress 

  Kthiri, Amena; Hidouri, Slah; Wiem, Tahri; Jeridi, Roua; Sheehan, David; Landouls, Ahmed (PLoS ONE, 2019-01-04)

  Exposure to static magnetic fields (SMF) can cause changes in microorganism metabolism altering key subcellular functions. The purpose of this study was to investigate whether an applied SMF could induce biological effects ...
• Retapamulin-assisted ribosome profiling reveals the alternative bacterial proteome 

  Meydan, Sezen; Marks, James; Klepacki, Dorota; Sharma, Virag; Baranov, Pavel V.; Firth, Andrew E.; Margus, Tonu; Kefi, Amira; Vázquez-Laslop, Nora; Mankin, Alexander S. (Elsevier Inc., 2019-03-20)

  The use of alternative translation initiation sites enables production of more than one protein from a single gene, thereby expanding the cellular proteome. Although several such examples have been serendipitously found ...

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