• IGF-1 receptor activity in the Golgi of migratory cancer cells depends on adhesion-dependent phosphorylation of Tyr1250 and Tyr1251 

  Rieger, Leonie; O’Shea, Sandra; Godsmark, Grant; Stanicka, Joanna; Kelly, Geraldine; O’Connor, Rosemary (American Association for the Advancement of Science, 2020-05-26)

  Although insulin-like growth factor 1 (IGF-1) signaling promotes tumor growth and cancer progression, therapies that target the IGF-1 receptor (IGF-1R) have shown poor clinical efficacy. To address IGF-1R activity in cancer ...
• Genotypic and phenotypic characterization of food-associated Lactobacillus plantarum isolates for potential probiotic activities. 

  Prete, Roberta; Long, Sarah L.; Joyce, Susan A.; Corsetti, Aldo (Oxford University Press, 2020-05-09)

  Lactic acid bacterium, Lactobacillus plantarum, has been applied, for centuries, for food and drink fermentations. Given the benefits associated with fermented products, Lb. plantarum strains have captured considerable ...
• Investigating the effects of oscillating sounds on the memory of older populations 

  Pfalzgraf, Hadley C. (2019-10-04)

  Introduction: Memory functions are associated with various oscillations of electrical activity in the brain, and disruptions of those rhythms can be observed in many neurological syndromes, including Alzheimer’s Disease. ...
• Regulated phase separation in nanopatterned protein-polysaccharide thin films by spin coating 

  Banta, Russell A.; Collins, Timothy W.; Curley, Ricky; O'Connell, John; Young, Paul W.; Holmes, Justin D.; Flynn, Eoin J. (Elsevier, 2020-03-18)

  Patterned films are essential to the commonplace technologies of modern life. However, they come at high cost to the planet, being produced from non-renewable, petrochemical-derived polymers and utilising substrates that ...
• Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease 

  Ryan, Fergal J.; Ahern, A. M.; Fitzgerald, R. S.; Laserna-Mendieta, E. J.; Power, E. M.; Clooney, A. G.; O'Donoghue, K. W.; McMurdie, P. J.; Iwai, S.; Crits-Christoph, A.; Sheehan, F.; Moran, C.; Flemer, B.; Zomer, A. L.; Fanning, A.; O'Callaghan, J.; Walton, Janette; Temko, Andriy; Stack, W.; Jackson, L.; Joyce, Susan A.; Melgar, Silvia; DeSantis, Todd Z.; Bell, Bell, Jordana T.; Shanahan, Fergus; Claesson, Marcus J. (Springer Nature, 2020-03-23)

  Studies of inflammatory bowel disease (IBD) have been inconclusive in relating microbiota with distribution of inflammation. We report microbiota, host transcriptomics, epigenomics and genetics from matched inflamed and ...

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