Biochemistry and Cell Biology

Biochemistry and Cell Biology

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  • Roche, Sarah L.; Wyse-Jackson, Alice C.; Ruiz-Lopez, Ana M.; Byrne, Ashleigh M.; Cotter, Thomas G. (Nature Publishing Group, 2017-02-20)
    Retinitis pigmentosa (RP) encompasses a group of retinal diseases resulting in photoreceptor loss and blindness. We have previously shown in the rd10 mouse model of RP, that rd10 microglia drive degeneration of viable ...
  • Kelly, Caroline Ann (University College Cork, 2017)
    For industrial applications, solid-state O2 sensors based on the quenching of photoluminescence, should be accurate, robust, easy-to-use in a calibration-free manner. These sensors generally consist of an O2 sensitive ...
  • Addario, Barbara; Sandblad, Linda; Persson, Karina; Backman, Lars (PeerJ, 2016-03-28)
    The actin cytoskeleton plays a fundamental role in eukaryotic cells. Its reorganization is regulated by a plethora of actin-modulating proteins, such as a-actinin. In higher organisms, α-actinin is characterized by the ...
  • Jenkins, James (University College Cork, 2016)
    This thesis presents the development and evaluation of new luminescent sensors and probes, optimisation of the tumour spheroid model and the various applications for these in vitro tissues combined with novel O2 and ...
  • Tzani, Ioanna (University College Cork, 2016)
    Cancer is the name given to diverse diseases, whose common characteristic is uncontrolled cell proliferation. In an effort to rationalise the complexity of cancer Hanahan and Weinberg (2000, 2011) proposed the hallmarks ...

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