Artemiuk, Patrycja Anna(University College Cork, 2019)
Rab11 GTPases are a family of three monomeric G proteins which are involved in a number of cellular processes including cell division, cell migration and cargo trafficking. Rab11a and Rab11b share over 89% sequence similarity, ...
Retinitis pigmentosa (RP) involves a group of hereditary diseases that cause progressive and severe visual impairment, with a prevalence of about 1 in 4,000 individuals worldwide. Unfortunately, there is currently no cure ...
Waschbüsch, Dieter; Hübel, Nicole; Ossendorf, Edith; Lobbestael, Evy; Baekelandt, Veerle; Lindsay, Andrew J.; McCaffrey, Mary W.; Khan, Amir R.; Barnekow, Angelika(Public Library of Science, 2019)
The Rab family of small GTPases regulate various aspects of cellular dynamics in eukaryotic cells. Membrane trafficking has emerged as central to the functions of leucine-rich repeat kinase 2 (LRRK2), which is associated ...
Hardy, Serge; Kostantin, Elie; Wang, Shan Jin; Hristova, Tzvetena; Galicia-Vázquez, Gabriela; Baranov, Pavel V.; Pelletier, Jerry; Tremblay, Michel L.(National Academy of Sciences, 2019-02-19)
The phosphatases of regenerative liver (PRL) have been shown to interact with the CNNM magnesium transport regulators. Through this protein complex, PRL controls the levels of intracellular magnesium. Our study uncovers a ...
Translation initiation is a complex process. The efficiency of translation initiation is determined not just by activity and availability of the translation initiation apparatus, but also the properties of mRNA 5’transcript ...
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