PINK1 (PTEN-induced putative kinase-1) functions as a ubiquitous serine-threonine kinase, with pro-survival, neuroprotective and anti-stress signalling functions. Autosomal recessive mutations in PINK1, resulting in a loss ...
Bifidobacteria are one of the first bacterial genera to colonise the gastrointestinal tract of human infants, are found in breast milk, are reported to influence immunity and to affect susceptibility to infectious and ...
Kiniry, Stephen J.; Michel, Audrey M.; Baranov, Pavel V.(John Wiley & Sons, Inc., 2019-11-24)
Since the introduction of the ribosome profiling technique in 2009 its popularity has greatly increased. It is widely used for the comprehensive assessment of gene expression and for studying the mechanisms of regulation ...
Hepatitis C Virus (HCV) mainly infects liver hepatocytes and replicates its single-stranded plus strand RNA genome exclusively in the cytoplasm. Viral proteins and RNA interfere with the host cell immune response, allowing ...
Nutrient-sensitive phosphorylation of the S6 protein of the 40S subunit of the eukaryote ribosome is highly conserved. However, despite four decades of research, the functional consequences of this modification remain ...
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