• The microbiome-gut-brain axis in preclinical alpha-synuclein models of Parkinson's disease 

  O'Donovan, Sarah (University College Cork, 2019)

  Parkinson’s disease (PD) is a progressive irreversible neurodegenerative disorder with no preventative treatment. PD is a multisystem disorder, affecting both central and peripheral nervous systems and is characterised by ...
• A genetic code expansion: investigation of UGA stop codon redefinition in selenoproteins 

  Baclaocos, Janinah (University College Cork, 2019)

  After the genetic code was deciphered in the 1960s, Francis Crick formulated the ‘frozen accident’ hypothesis (Crick, 1968) to describe the origins of the genetic code as universal and resistant to change or evolution. ...
• Investigation of mechanisms underpinning host-microbial interactions in the gastrointestinal tract 

  Udayan, Sreeram (University College Cork, 2019)

  Research in the areas of microbiome science and immunology have identified different members of a host’s microbiota, particularly bacteria, as having critical roles in shaping the development and function of both intestinal ...
• New biosensors for metabolic imaging 

  O'Donnell, Neil (University College Cork, 2018)

  Tissue engineering is a multi-disciplinary field that involves three-dimensional cell and tissue models, live cell microscopy and related imaging modalities, along with fluorescence and phosphorescence-based biosensors. ...
• A functional analysis of Rab11a and Rab11b in endosomal recycling 

  Artemiuk, Patrycja A. (University College Cork, 2019)

  Rab11 GTPases are a family of three monomeric G proteins which are involved in a number of cellular processes including cell division, cell migration and cargo trafficking. Rab11a and Rab11b share over 89% sequence similarity, ...

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