Long-term colonisation with donor bacteriophages following successful faecal microbial transplantation

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Long-term colonisation with donor bacteriophages following successful faecal microbial transplantation

Draper, Lorraine A.; Ryan, Feargal J.; Smith, Muireann K.; Jalanka, J.; Mattila, E.; Arkkila, P.A.; Ross, R. Paul; Satokari, R.; Hill, Colin
Date: 2018-12-10
Copyright: © 2018 The Author(s)
Copyright information: https://creativecommons.org/licenses/by/4.0/
Related: https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-018-0598-x
Citation: Draper, L.A., Ryan, F.J., Smith, M.K., Jalanka, J., Mattila, E., Arkkila, P.A., Ross, R.P., Satokari, R. and Hill, C., 2018. Long-term colonisation with donor bacteriophages following successful faecal microbial transplantation. Microbiome, 6(1). (9pp) DOI: 10.1186/s40168-018-0598-x
Published Version: 10.1186/s40168-018-0598-x

Abstract:

Faecal microbiota transplantation (FMT) is used in the treatment of recurrent Clostridium difficile infection. Its success is typically attributed to the restoration of a diverse microbiota. Viruses (including bacteriophages) are the most numerically dominant and potentially the most diverse members of the microbiota, but their fate following FMT has not been well studied.

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