Long-term colonisation with donor bacteriophages following successful faecal microbial transplantation
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Published version
Date
2018-12-10
Authors
Draper, Lorraine A.
Ryan, Feargal J.
Smith, Muireann K.
Jalanka, J.
Mattila, E.
Arkkila, P.A.
Ross, R. Paul
Satokari, R.
Hill, Colin
Journal Title
Journal ISSN
Volume Title
Publisher
BMC part of Springer Nature
Published Version
Abstract
Faecal microbiota transplantation (FMT) is used in the treatment of recurrent Clostridium difficile infection. Its success is typically attributed to the restoration of a diverse microbiota. Viruses (including bacteriophages) are the most numerically dominant and potentially the most diverse members of the microbiota, but their fate following FMT has not been well studied.
Description
Keywords
Faecal microbiota transplantation , Bacteriophages , Viruses , Engraftment , Persistence , Donor-recipient
Citation
Draper, L.A., Ryan, F.J., Smith, M.K., Jalanka, J., Mattila, E., Arkkila, P.A., Ross, R.P., Satokari, R. and Hill, C., 2018. Long-term colonisation with donor bacteriophages following successful faecal microbial transplantation. Microbiome, 6(1). (9pp) DOI: 10.1186/s40168-018-0598-x