• Tipping phenomena and points of no return in ecosystems: beyond classical bifurcations 

  O'Keefe, Paul E.; Wieczorek, Sebastian (Society for Industrial and Applied Mathematic, SIAM, 2020-10-22)

  We discuss tipping phenomena in nonautonomous systems using an example of a bistable ecosystem model with environmental changes represented by time-varying parameters [Scheffer et al., Ecosystems, 11 (2008), pp. 275--279]. ...
• Gut microbiota composition correlates with diet and health in the elderly 

  Claesson, Marcus J.; Jeffery, Ian B.; Conde, Susana; Power, Susan E.; O'Connor, Eibhlí­s M.; Cusack, Siobhán; Harris, Hugh M. B.; Coakley, Mairead; Lakshminarayanan, Bhuvaneswari; O'Sullivan, Orla; Fitzgerald, Gerald F.; Deane, Jennifer; O'Connor, Michael; Harnedy, Norma; O'Connor, Kieran; O'Mahony, Denis; van Sinderen, Douwe; Wallace, Martina; Brennan, Lorraine; Stanton, Catherine; Marchesi, Julian R.; Fitzgerald, Anthony P.; Shanahan, Fergus; Hill, Colin; Ross, R. Paul; O'Toole, Paul W. (Macmillan Publishers Limited, 2012-07-13)

  Alterations in intestinal microbiota composition are associated with several chronic conditions, including obesity and inflammatory diseases. The microbiota of older people displays greater inter-individual variation than ...
• An exploration of the prognostic utility of shortened dynamic imaging protocols for PET-FDG scans 

  Wu, Qi; O'Sullivan, Finbarr; Muzi, Mark; Mankoff, David (Institute of Electrical and Electronics Engineers (IEEE), 2019-11)

  Standard whole-body clinical fluoro-deoxyglucose (FDG)-PET scans typically involve imaging for around 15 minutes about 60 minutes after tracer injection. The scan duration is often the critical constraint limiting patient ...
• A simple evaluation of the benefit of combined kinetic analysis of multiple injection dynamic PET scans 

  Gu, Fengyun; O'Sullivan, Finbarr; Muzi, Mark; Mankoff, David A. (Institute of Electrical and Electronics Engineers (IEEE), 2019-11)

  The multiple injection dynamic Positron Emission Tomography (PET) scanning is used in the clinical management of certain groups of cancer patients and in medical research. The analysis of such studies can be approached in ...
• An illustration of the use of model-based bootstrapping for evaluation of uncertainty in kinetic information derived from dynamic PET 

  Gu, Fengyun; Wu, Qi; O'Sullivan, Finbarr; Huang, Jian; Muzi, Mark; Mankoff, David A. (Institute of Electrical and Electronics Engineers (IEEE), 2019-11)

  Kinetic mapping via mixture analysis[8], [10] involves comprehensive voxel-level analysis of dynamic PET data. Bootstrapping from the fitted mixture model gives the ability to directly simulate statistical copies of the ...

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