Emerging areas of personalized medicine in Obstetrics and Gynaecology: a narrative review

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dc.contributor.authorLeung, Roxanne H.
dc.contributor.authorBelfiore, Alyssa
dc.contributor.authorWhibbs, Hannah
dc.contributor.authorWilson, Emma
dc.contributor.authorSeo, Hoyang
dc.contributor.authorRotman, Sydney
dc.date.accessioned2024-09-12T10:32:40Z
dc.date.available2024-09-12T10:32:40Z
dc.date.issued2024
dc.description.abstractImportance: Obstetrics and gynaecology (OBGYN) focuses on women’s reproductive health. Many significant challenges in the field of OBGYN stem from limitations in screening, diagnostic, or treatment options. Conditions that are poorly understood, such as pre-eclampsia or endometriosis offer few management options or prevention strategies. In recent years, growing interest and advancements in personalized medicine have led to a deeper understanding of the aetiology and pathophysiology of OBGYN conditions, potential targets for intervention, and novel approaches to management. The aim of this review is to briefly describe some of these emerging areas of research and clinical use. Observations: Personalized medicine in obstetrics is a foundational concept underlying routine prenatal care and also drives ongoing research in areas such as advanced assisted reproductive technology, screening for medical complications during pregnancy, and fetal treatment in utero of congenital diseases. In gynaecology, developments in our understanding of determinants and mechanisms of common conditions have illuminated potential avenues for improved diagnosis and more individualized approaches to treatment of endometriosis and postmenopausal symptoms. Conclusions and Relevance: Personalized medicine is a flourishing area of research and clinical application with the potential for significant benefits to OBGYN patients. This concept has driven research interest and advancement in OBGYN disease processes that are poorly understood and offers potential novel diagnostic and treatment options for the future. With endless potential to improve the health outcomes of women and children, personalized approaches to screening, diagnosis, and management are worthwhile investments.en
dc.description.statusPeer-revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationLeung, R. H., Belfiore, A., Whibbs, H., Wilson, E., Seo, H. and Rotman, S. (2024) 'Emerging areas of personalized medicine in Obstetrics and Gynaecology: a narrative review', UCC Student Medical Journal, 4, pp. 127-130. https://doi.org/10.33178/SMJ.2024.1.18en
dc.identifier.doihttps://doi.org/10.33178/SMJ.2024.1.18
dc.identifier.endpage130
dc.identifier.issn2737-7237
dc.identifier.journalabbrevUCC SMJ
dc.identifier.journaltitleUCC Student Medical Journalen
dc.identifier.startpage127
dc.identifier.urihttps://hdl.handle.net/10468/16354
dc.identifier.urihttps://journals.ucc.ie/index.php/smj/article/view/4103
dc.language.isoenen
dc.publisherUCC Medical Research and Technology Societyen
dc.rights© 2024, the Author(s). This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.en
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0
dc.sourceBatch uploaden
dc.subjectPersonalized medicineen
dc.subjectPrecision medicineen
dc.subjectNarrative reviewen
dc.subjectObstetricsen
dc.subjectGynaecologyen
dc.titleEmerging areas of personalized medicine in Obstetrics and Gynaecology: a narrative reviewen
dc.typeArticle (peer-reviewed)en
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