EAACI guideline: Anaphylaxis (2021 update).

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dc.check.date2022-08-03
dc.check.infoAccess to this article is restricted until 12 months after publication by request of the publisher.en
dc.contributor.authorMuraro, A.
dc.contributor.authorWorm, M.
dc.contributor.authorAlviani, C.
dc.contributor.authorCardona, V.
dc.contributor.authorDunn Galvin, Audrey
dc.contributor.authorGarvey, L. H.
dc.contributor.authorRiggioni, C.
dc.contributor.authorde Silva, D.
dc.contributor.authorAngier, E.
dc.contributor.authorArasi, S.
dc.contributor.authorBellou, A.
dc.contributor.authorBeyer, K.
dc.contributor.authorBijlhout, D.
dc.contributor.authorBilò, M. B.
dc.contributor.authorBindslev-Jensen, C.
dc.contributor.authorBrockow, K.
dc.contributor.authorFernandez-Rivas, M.
dc.contributor.authorHalken, S.
dc.contributor.authorJensen, B.
dc.contributor.authorKhaleva, E.
dc.contributor.authorMichaelis, L. J.
dc.contributor.authorOude Elberink, H. N. G.
dc.contributor.authorRegent, L.
dc.contributor.authorSanchez, A.
dc.contributor.authorVlieg-Boerstra, B. J.
dc.contributor.authorRoberts, G.
dc.date.accessioned2021-08-13T13:22:09Z
dc.date.available2021-08-13T13:22:09Z
dc.date.issued2021-08-03
dc.date.updated2021-08-13T11:13:33Z
dc.description.abstractAnaphylaxis is a clinical emergency which all healthcare professionals need to be able to recognise and manage. The European Academy of Allergy and Clinical Immunology Anaphylaxis multidisciplinary Task Force has updated the 2014 guideline. The guideline was developed using the AGREE II framework and the GRADE approach. The evidence was systematically reviewed and recommendations were created by weighing up benefits and harms. The guideline was peer-reviewed by external experts and reviewed in a public consultation. The use of clinical criteria to identify anaphylaxis is suggested with blood sampling for the later measurement of tryptase. The prompt use of intramuscular adrenaline as first line management is recommended with the availability of adrenaline autoinjectors to patients in the community. Pharmacokinetic data should be provided for adrenaline autoinjector devices. Structured, comprehensive training for people at risk of anaphylaxis is recommended. Simulation training and visual prompts for healthcare professionals are suggested to improve the management of anaphylaxis. It is suggested that school policies reflect anaphylaxis guidelines. The evidence for the management of anaphylaxis remains mostly at a very low level. There is an urgent need to prioritise clinical trials with the potential to improve the management of patients at risk of anaphylaxis.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationMuraro, A., Worm, M., Alviani, C., Cardona, V., Dunn Galvin, A., Garvey, L. H., Riggioni, C., de Silva, D., Angier, E., Arasi, S., Bellou, A., Beyer, K., Bijlhout, D., Bilò, M. B., Bindslev-Jensen, C., Brockow, K., Fernandez-Rivas, M., Halken, S., Jensen, B., Khaleva, E., Michaelis, L. J., Oude Elberink, H. N. G., Regent, L., Sanchez, A., Vlieg-Boerstra, B. J. and Roberts, G. (2021) 'EAACI guideline: Anaphylaxis (2021 update)', Allergy. doi: 10.1111/all.15032en
dc.identifier.doi10.1111/all.15032en
dc.identifier.eissn1398-9995
dc.identifier.issn0105-4538
dc.identifier.journaltitleAllergyen
dc.identifier.urihttps://hdl.handle.net/10468/11740
dc.language.isoenen
dc.publisherJohn Wiley & Sons, Inc.en
dc.rights© 2020, EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd. This is the peer reviewed version of the following article: Muraro, A., Worm, M., Alviani, C., Cardona, V., Dunn Galvin, A., Garvey, L. H., Riggioni, C., de Silva, D., Angier, E., Arasi, S., Bellou, A., Beyer, K., Bijlhout, D., Bilò, M. B., Bindslev-Jensen, C., Brockow, K., Fernandez-Rivas, M., Halken, S., Jensen, B., Khaleva, E., Michaelis, L. J., Oude Elberink, H. N. G., Regent, L., Sanchez, A., Vlieg-Boerstra, B. J. and Roberts, G. (2021) 'EAACI guideline: Anaphylaxis (2021 update)', Allergy, doi: 10.1111/all.15032, which has been published in final form at: https://doi.org/10.1111/all.15032. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.en
dc.subjectAnaphylaxisen
dc.subjectAdultsen
dc.subjectChildrenen
dc.subjectGuidelinesen
dc.titleEAACI guideline: Anaphylaxis (2021 update).en
dc.typeArticle (peer-reviewed)en
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