A rare cause of otalgia - Langerhans Cell Histiocytosis case report

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dc.contributor.authorAlbakri, Ahmaden
dc.contributor.authorMurphy, Claudineen
dc.contributor.authorMcWilliams, Sebastianen
dc.contributor.authorO'Cathain, Eadoinen
dc.contributor.editorMehta, Shobhaen
dc.contributor.editorCronin, Pádraigen
dc.date.accessioned2025-10-28T13:55:03Z
dc.date.available2025-10-28T13:55:03Z
dc.date.issued2025en
dc.description.abstractBackground: Langerhans Cell Histiocytosis (LCH) is a myeloid neoplastic disorder with a rare prevalence of one case per million adults. LCH has a complicated etiology that presents as lesions composed of proliferative ‘LCH cells’. These lesions can affect different organ systems including the lungs, skin, liver, and bone. This study reports the steps toward LCH diagnosis in an adult, the current state of literature in regards to LCH of the temporal bone, and important takeaways for ENT physicians. Case Report: We describe the case of a 52 year old woman with a two year history of seemingly idiopathic Central Diabetes Insipidus (CDI) complaining of right otalgia for two weeks unresponsive to antibiotic therapy. The patient has a normal otoscopy and audiogram, and an elevated CRP test (22 mg/dl). Further investigations with CT and MRI confirmed destruction of the right mastoid air cells and enhancing tissue respectively. Cholesteatoma was ruled out with diffusion weighted imaging on MRI. Cortical mastoidectomyen
dc.description.statusNot peer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationAlbakri, A., Murphy, C., McWilliams, S. and O'Cathain, E. (2025) 'A rare cause of otalgia - Langerhans Cell Histiocytosis case report', UCC Student Medical Journal, 5, p. 104. https://doi.org/10.33178/SMJ.2025.1.30en
dc.identifier.doi10.33178/SMJ.2025.1.30en
dc.identifier.endpage104en
dc.identifier.issn2737-7237
dc.identifier.journalabbrevUCC SMJ
dc.identifier.journaltitleUCC Student Medical Journalen
dc.identifier.startpage104en
dc.identifier.urihttps://hdl.handle.net/10468/18107
dc.identifier.volume5
dc.language.isoenen
dc.publisherUCC Medical Research and Technology Societyen
dc.rights© 2025, the Author(s). This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.en
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0
dc.sourceBatch uploaden
dc.subjectOtalgiaen
dc.subjectLangerhans Cell Histiocytosisen
dc.subjectCase reporten
dc.titleA rare cause of otalgia - Langerhans Cell Histiocytosis case reporten
dc.typeConference itemen
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