Combination of diffuse reflectance and transmittance spectroscopy to obtain optical properties of liquid phantoms

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dc.contributor.authorGunther, Jacqueline
dc.contributor.authorLu, Huihui
dc.contributor.authorAndersson-Engels, Stefan
dc.contributor.funderScience Foundation Irelanden
dc.date.accessioned2020-03-11T11:10:41Z
dc.date.available2020-03-11T11:10:41Z
dc.date.issued2020-02-22
dc.date.updated2020-03-11T10:17:09Z
dc.description.abstractWe present a simple fiber-optics probe system that could be used in any lab for convenient determination of optical properties of liquid phantoms based on diffuse reflectance and transmittance measurements in the visible/near-infrared region. We employed Monte Carlo simulations to determine the optimal system setup and to test the inverse algorithm employed to extract the optical properties from measured reflectance and transmittance. The inverse algorithm involved obtaining the fit merit function for values within the optical property range and determining the minimum. The performance of the method was tested by predictive error and validated using similar matrix of milk–ink phantoms on reflectance and transmittance. In the range of optical properties of phantoms with optical properties of 0 to 0.5 cm−1 for μa and 20 to 140 cm−1 for μs, the median prediction error for the test phantoms at 630 nm was 1.51% for μs and 8.82% for μa. The median difference in predicted values versus expected values was 1.15 cm−1 for μs and 0.01 cm−1 for μa. In comparison with other techniques, our method was a simple, fast, and convenient way to determine optical properties of liquid phantoms.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleid24109en
dc.identifier.citationGunther, J., Lu, H. and Andersson-Engels, S. (2020) 'Combination of diffuse reflectance and transmittance spectroscopy to obtain optical properties of liquid phantoms', Optical Engineering, 59(2), 24109 (12pp). doi: 10.1117/1.OE.59.2.024109en
dc.identifier.doi10.1117/1.OE.59.2.024109en
dc.identifier.eissn1560-230
dc.identifier.endpage12en
dc.identifier.issn0091-3286
dc.identifier.issued2en
dc.identifier.journaltitleOptical Engineeringen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/9750
dc.identifier.volume59en
dc.language.isoenen
dc.publisherSociety of Photo-optical Instrumentation Engineers (SPIE)en
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Research Professorship Programme/15/RP/2828/IE/Novel applications and techniques for in vivo optical imaging and spectroscopy/en
dc.rights© 2020, the Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI. [DOI: 10.1117/1.OE.59.2.024109]en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectOptical propertiesen
dc.subjectSpectroscopyen
dc.subjectFiber-opticsen
dc.subjectPhantomsen
dc.titleCombination of diffuse reflectance and transmittance spectroscopy to obtain optical properties of liquid phantomsen
dc.typeArticle (peer-reviewed)en
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