Advances in the synthesis of acyclic peroxides

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dc.contributor.authorO'Sullivan, Timothy P.
dc.contributor.authorGandhi, Hirenkumar
dc.contributor.authorO'Reilly, Kate
dc.contributor.authorGupta, Manoj K.
dc.contributor.authorHorgan, Conor C.
dc.contributor.authorO'Leary, Eileen M.
dc.contributor.funderIrish Research Councilen
dc.contributor.funderEuropean Commissionen
dc.contributor.funderSeventh Framework Programmeen
dc.date.accessioned2017-05-09T09:35:05Z
dc.date.available2017-05-09T09:35:05Z
dc.date.issued2017-03-31
dc.date.updated2017-05-09T09:21:12Z
dc.description.abstractPeroxide-containing compounds are an attractive synthetic target, given their widespread abundance in nature, with many displaying potent antimalarial and antimicrobial properties. This review summarises the many developments in the synthesis of acyclic peroxides, with a particular focus on the past 20 years, and seeks to update organic chemists about these new approaches. The synthetic methodologies have been subdivided into metal-catalysed reactions, organocatalytic reactions, direct oxidation reactions, miscellaneous reactions and enzymatic routes to acyclic peroxides.en
dc.description.sponsorshipIrish Research Council (IRCGOIPG/2013/113)en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationGandhi, H., O'Reilly, K., Gupta, M. K., Horgan, C., O'Leary, E. M. and O'Sullivan, T. P. (2017) 'Advances in the synthesis of acyclic peroxides', RSC Advances, 7(32), pp. 19506-19556. doi:10.1039/C6RA28489Ben
dc.identifier.doi10.1039/C6RA28489B
dc.identifier.endpage19556en
dc.identifier.issn2046-2069
dc.identifier.issued32en
dc.identifier.journaltitleRSC Advancesen
dc.identifier.startpage19506en
dc.identifier.urihttps://hdl.handle.net/10468/3931
dc.identifier.volume7en
dc.language.isoenen
dc.publisherRoyal Society of Chemistryen
dc.relation.projectinfo:eu-repo/grantAgreement/EC/FP7::SP3::PEOPLE/272194/EU/Towards an enantioselective synthesis of Plakortide P and its application to the development of drugs for the treatment of Chagas disease/PLAKORTIDEen
dc.rights© The Royal Society of Chemistry 2017. This Open Access Article is licensed under a Creative Commons Attribution 3.0 Unported Licenceen
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/en
dc.subjectAcyclic peroxidesen
dc.subjectSynthesisen
dc.subjectSynthetic methodologiesen
dc.titleAdvances in the synthesis of acyclic peroxidesen
dc.typeArticle (peer-reviewed)en
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