Preventing and Lessening Exacerbations of Asthma in School-aged children Associated with a New Term (PLEASANT): recruiting primary care research sites - the PLEASANT experience
| dc.contributor.author | Horspool, Michelle J. | |
| dc.contributor.author | Julious, Steven A. | |
| dc.contributor.author | Mooney, Cara | |
| dc.contributor.author | May, Robin | |
| dc.contributor.author | Sully, Ben | |
| dc.contributor.author | Smithson, W. Henry | |
| dc.contributor.funder | National Institute for Health Research | en |
| dc.date.accessioned | 2018-10-08T08:30:24Z | |
| dc.date.available | 2018-10-08T08:30:24Z | |
| dc.date.issued | 2015-11-12 | |
| dc.date.updated | 2018-10-05T11:55:55Z | |
| dc.description.abstract | Background: Recruitment of general practices and their patients into research studies is frequently reported as a challenge. The Preventing and Lessening Exacerbations of Asthma in School-aged children Associated with a New Term (PLEASANT) trial recruited 142 general practices, across England and Wales and delivered the study intervention to time and target. Aims: To describe the process of recruitment used within the cluster randomised PLEASANT trial and present results on factors that influenced recruitment. Methods: Data were collected on the number of and types of contact used to gain expression of interest and subsequent randomisation into the PLEASANT trial. Practice size and previous research experience were also collected. Results: The mean number of contacts required to gain expression of interest were m=3.01 (s.d. 1.6) and total number of contacts from initial invitation to randomisation m=6.8 (s.d. 3.5). Previous randomised controlled trial involvement (hazard ratio (HR)=1.81 (confidence interval (CI) 95%, 1.55–2.11) P<0.001) and number of studies a practice had previously engaged in (odds ratio (OR) 1.91 (CI 95%, (1.52–2.42)) P<0.001), significantly influenced whether a practice would participate in PLEASANT. Practice size was not a significant deciding factor (OR=1.04 (95% CI 0.99–1.08) P=0.137). Conclusions: Recruitment to time and target can be achieved in general practice. The amount of resource required for site recruitment should not, however, be underestimated and multiple strategies for contacting practices should be considered. General practitioners with more research experience are more likely to participate in studies. | en |
| dc.description.sponsorship | National Institute for Health Research (Health Technology Assessment Programme: project number 11/01/10) | en |
| dc.description.status | Peer reviewed | en |
| dc.description.version | Published Version | en |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.articleid | 15066 | |
| dc.identifier.citation | Horspool, M. J., Julious, S. A., Mooney, C., May, R., Sully, B. and Smithson, W. H. (2015) 'Preventing and Lessening Exacerbations of Asthma in School-aged children Associated with a New Term (PLEASANT): recruiting primary care research sites - the PLEASANT experience', npj Primary Care Respiratory Medicine, 25, 15066 (5pp). doi:10.1038/npjpcrm.2015.66 | en |
| dc.identifier.doi | 10.1038/npjpcrm.2015.66 | |
| dc.identifier.issn | 2055-1010 | |
| dc.identifier.journaltitle | npj Primary Care Respiratory Medicine | en |
| dc.identifier.uri | https://hdl.handle.net/10468/6986 | |
| dc.identifier.volume | 25 | en |
| dc.language.iso | en | en |
| dc.publisher | Springer Nature Ltd. | en |
| dc.rights | © 2015, Primary Care Respiratory Society UK/Macmillan Publishers Limited. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ | en |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en |
| dc.subject | General practice | en |
| dc.subject | Research studies | en |
| dc.subject | Trial | en |
| dc.subject | Resource | en |
| dc.subject | Recruitment | en |
| dc.title | Preventing and Lessening Exacerbations of Asthma in School-aged children Associated with a New Term (PLEASANT): recruiting primary care research sites - the PLEASANT experience | en |
| dc.type | Article (peer-reviewed) | en |
