The origin of shape sensitivity in palladium-catalyzed Suzuki–Miyaura cross coupling reactions

Collins, Gillian; Schmidt, Michael; O'Dwyer, Colm; Holmes, Justin D.; McGlacken, Gerard P.

The origin of shape sensitivity in palladium-catalyzed Suzuki–Miyaura cross coupling reactions

dc.contributor.author	Collins, Gillian
dc.contributor.author	Schmidt, Michael
dc.contributor.author	O'Dwyer, Colm
dc.contributor.author	Holmes, Justin D.
dc.contributor.author	McGlacken, Gerard P.
dc.contributor.funder	Enterprise Ireland	en
dc.contributor.funder	Eli Lilly and Company, United States	en
dc.contributor.funder	Johnson Matthey Plc, United Kingdom
dc.date.accessioned	2016-02-29T09:30:13Z
dc.date.available	2016-02-29T09:30:13Z
dc.date.issued	2014-03-11
dc.date.updated	2014-04-15T12:39:35Z
dc.description.abstract	The shape sensitivity of Pd catalysts in Suzuki–Miyaura coupling reactions is studied using nanocrystals enclosed by well-defined surface facets. The catalytic performance of Pd nanocrystals with cubic, cuboctahedral and octahedral morphologies are compared. Superior catalytic reactivity is observed for Pd NCs with {100} surface facets compared to {111} facets. The origin of the enhanced reactivity associated with a cubic morphology is related to the leaching susceptibility of the nanocrystals. Molecular oxygen plays a key role in facilitating the leaching of Pd atoms from the surface of the nanocrystals. The interaction of O2 with Pd is itself facet-dependent, which in turn gives rise to more efficient leaching from {100} facets, compared to {111} facets under the reaction conditions.	en
dc.description.sponsorship	Enterprise Ireland (EI2011-023)	en
dc.description.status	Peer reviewed	en
dc.description.version	Accepted Version	en
dc.format.mimetype	application/pdf	en
dc.identifier.citation	COLLINS, G., SCHMIDT, M., O'DWYER, C., HOLMES, J. D. & MCGLACKEN, G. P. 2014. The Origin of Shape Sensitivity in Palladium-Catalyzed Suzuki–Miyaura Cross Coupling Reactions. Angewandte Chemie International Edition, 53, 4142-4145. http://dx.doi.org/10.1002/anie.201400483	en
dc.identifier.doi	10.1002/anie.201400483
dc.identifier.endpage	4145	en
dc.identifier.issn	1433-7851
dc.identifier.issued	16	en
dc.identifier.journaltitle	Angewandte Chemie International Edition	en
dc.identifier.startpage	4142	en
dc.identifier.uri	https://hdl.handle.net/10468/2410
dc.identifier.volume	53	en
dc.language.iso	en	en
dc.publisher	Wiley-VCH	en
dc.relation.uri	http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1521-3773
dc.rights	© 2014 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. This is the peer reviewed version of the following article: Collins, G., Schmidt, M., O'Dwyer, C., Holmes, J. D. and McGlacken, G. P. (2014), The Origin of Shape Sensitivity in Palladium-Catalyzed Suzuki–Miyaura Cross Coupling Reactions. Angew. Chem. Int. Ed., 53: 4142-4145which has been published in final form at doi: 10.1002/anie.201400483. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.	en
dc.subject	Heterogeneous catalysis	en
dc.subject	Palladium	en
dc.subject	Surface facet	en
dc.subject	Suzuki–Miyaura coupling	en
dc.subject	Catalysis	en
dc.subject	Leaching	en
dc.subject	Nanocrystals	en
dc.subject	Palladium	en
dc.subject	Catalytic performance	en
dc.subject	Catalytic reactivity	en
dc.subject	Cross coupling reactions	en
dc.subject	Enhanced reactivity	en
dc.subject	Octahedral morphology	en
dc.subject	Shape sensitivities	en
dc.title	The origin of shape sensitivity in palladium-catalyzed Suzuki–Miyaura cross coupling reactions	en
dc.type	Article (peer-reviewed)	en