Human intestinal microbiota and metabolites they produce in relation to host health

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dc.check.opt-outNoen
dc.contributor.advisorFitzgerald, Gerald F.en
dc.contributor.advisorStanton, Catherineen
dc.contributor.advisorRoss, R. Paulen
dc.contributor.authorRussell, David A.
dc.contributor.funderScience Foundation Irelanden
dc.contributor.funderAPC Microbiome Institute, College of Medicine and Health, University College Corken
dc.contributor.funderTeagasc
dc.date.accessioned2015-01-19T12:35:33Z
dc.date.issued2014
dc.date.submitted2014
dc.description.abstractThe aim of this thesis was to identify selected potential probiotic characteristics of Bifidobacterium longum strains isolated from human sources, and to examine these characteristics in detail using genomic and phenotypic techniques. One strain in particular Bifidobacterium longum DPC 6315 was the main focus of the thesis and this strain was used in both the manufacture of yoghurt and an animal study. In total, 38 B. longum strains, obtained from infants and adults, were assessed in vitro for the selected probiotic traits using a combined phenotypic and molecular approach. Differentiation of the 38 strains using amplified ribosomal DNA restriction analysis (ARDRA) into subspecies indicated that of the 38 bifidobacterial strains tested, 34 were designated B. longum subsp. longum and four B. longum subsp. infantis.en
dc.description.statusNot peer revieweden
dc.description.versionAccepted Version
dc.format.mimetypeapplication/pdfen
dc.identifier.citationRussell, D. A. 2014. Human intestinal microbiota and metabolites they produce in relation to host health. PhD Thesis, University College Cork.en
dc.identifier.endpage286en
dc.identifier.urihttps://hdl.handle.net/10468/1761
dc.language.isoenen
dc.publisherUniversity College Corken
dc.rights© 2014, David Russellen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/en
dc.subjectBifidobacteriaen
dc.subjectProbioticen
dc.subjectMetabolic activitiesen
dc.subjectHuman healthen
dc.subjectFood applicationsen
dc.thesis.opt-outfalse
dc.titleHuman intestinal microbiota and metabolites they produce in relation to host healthen
dc.typeDoctoral thesisen
dc.type.qualificationlevelDoctoralen
dc.type.qualificationnamePhD (Food Science and Technology)en
ucc.workflow.supervisorg.fitzgerald@ucc.ie
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