Bacterial toxins: Offensive, defensive, or something else altogether?

Simple item page
dc.contributor.authorRudkin, Justine K.
dc.contributor.authorMcLoughlin, Rachel M.
dc.contributor.authorPreston, Andrew
dc.contributor.authorMassey, Ruth C.
dc.date.accessioned2017-12-08T13:33:46Z
dc.date.available2017-12-08T13:33:46Z
dc.date.issued2017-09-21
dc.description.abstractThe secretion of proteins that damage host tissue is well established as integral to the infectious processes of many bacterial pathogens. However, recent advances in our understanding of the activity of toxins suggest that the attributes we have assigned to them from early in vitro experimentation have misled us into thinking of them as merely destructive tools. Here, we will discuss the multifarious ways in which toxins contribute to the lifestyle of bacteria and, by considering their activity from an evolutionary perspective, demonstrate how this extends far beyond their ability to destroy host tissueen
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleide1006452
dc.identifier.citationRudkin, J. K., McLoughlin, R. M., Preston, A. and Massey, R. C. (2017) 'Bacterial toxins: Offensive, defensive, or something else altogether?', PLOS Pathogens, 13(9), e1006452 (12pp). doi: 10.1371/journal.ppat.1006452en
dc.identifier.doi10.1371/journal.ppat.1006452
dc.identifier.endpage12
dc.identifier.issn1553-7366
dc.identifier.issn1553-7374
dc.identifier.issued9
dc.identifier.journaltitlePLOS Pathogensen
dc.identifier.startpage1
dc.identifier.urihttps://hdl.handle.net/10468/5150
dc.identifier.volume13
dc.language.isoenen
dc.publisherPublic Library of Scienceen
dc.relation.urihttp://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006452
dc.rights© 2017, Rudkin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectToxinsen
dc.subjectBacterial pathogensen
dc.subjectBacterial biofilmsen
dc.subjectStaphylococcus aureusen
dc.subjectHost cellsen
dc.subjectBiofilmsen
dc.subjectBordetella pertussisen
dc.subjectNoseen
dc.titleBacterial toxins: Offensive, defensive, or something else altogether?en
dc.typeArticle (peer-reviewed)en
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
3851.pdf
Size:
2.44 MB
Format:
Adobe Portable Document Format
Description:
Published Version
Download
Collections
Microbiology - Journal Articles