Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study

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dc.check.date2019-12-31
dc.check.infoAccess to this article is restricted until 12 months after publication by request of the publisher.en
dc.contributor.authorMenditto, E.
dc.contributor.authorCosta, Elisio
dc.contributor.authorMidão, L.
dc.contributor.authorBosnic-Anticevich, Sinthia Z.
dc.contributor.authorNovellino, E.
dc.contributor.authorBialek, S.
dc.contributor.authorBriedis, V.
dc.contributor.authorMair, A.
dc.contributor.authorRajabian-Soderlund, R.
dc.contributor.authorArnavielhe, S.
dc.contributor.authorBedbrook, A.
dc.contributor.authorCzarlewski, Wienczyslawa
dc.contributor.authorAnnesi-Maesano, I.
dc.contributor.authorAnto, J. M.
dc.contributor.authorDevillier, P.
dc.contributor.authorDe Vries, G.
dc.contributor.authorKeil, T.
dc.contributor.authorSheikh, A.
dc.contributor.authorOrlando, V.
dc.contributor.authorLarenas-Linnemann, D.
dc.contributor.authorCecchi, Lorenzo
dc.contributor.authorDe Feo, G.
dc.contributor.authorIllario, M.
dc.contributor.authorStellato, C.
dc.contributor.authorFonseca, J.
dc.contributor.authorMalva, J.
dc.contributor.authorMorais-Almeida, M.
dc.contributor.authorPereira, A. M.
dc.contributor.authorTodo-Bom, A.
dc.contributor.authorKvedariene, V.
dc.contributor.authorValiulis, A.
dc.contributor.authorBergmann, K. C.
dc.contributor.authorKlimek, L.
dc.contributor.authorMösges, R.
dc.contributor.authorPfaar, O.
dc.contributor.authorZuberbier, T.
dc.contributor.authorCardona, Victòria
dc.contributor.authorMullol, J.
dc.contributor.authorPapadopoulos, N. G.
dc.contributor.authorProkopakis, E. P.
dc.contributor.authorBewick, M.
dc.contributor.authorRyan, D.
dc.contributor.authorRoller-Wirnsberger, R. E.
dc.contributor.authorTomazic, P. V.
dc.contributor.authorCruz, A. A.
dc.contributor.authorKuna, P.
dc.contributor.authorSamolinski, B.
dc.contributor.authorFokkens, W. J.
dc.contributor.authorReitsma, S.
dc.contributor.authorBosse, Isabelle
dc.contributor.authorFontaine, J. F.
dc.contributor.authorLaune, D.
dc.contributor.authorHaahtela, T.
dc.contributor.authorToppila-Salmi, S.
dc.contributor.authorBachert, C.
dc.contributor.authorHellings, P. W.
dc.contributor.authorMelén, E.
dc.contributor.authorWickman, M.
dc.contributor.authorBindslev-Jensen, Carsten
dc.contributor.authorEller, Esben
dc.contributor.authorO'Hehir, R. E.
dc.contributor.authorCingi, C.
dc.contributor.authorGemicioglu, B.
dc.contributor.authorKalayci, O.
dc.contributor.authorIvancevich, J. C.
dc.contributor.authorBousquet, J.
dc.contributor.authorHourihane, Jonathan O'B.
dc.contributor.authorthe MASK group
dc.date.accessioned2019-01-09T09:27:32Z
dc.date.available2019-01-09T09:27:32Z
dc.date.issued2018-12-31
dc.date.updated2019-01-08T12:49:54Z
dc.description.abstractBackground: Mobile technology may help to better understand the adherence to treatment MASK‐rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient‐centered ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries. Objectives: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App. Methods: An observational cross‐sectional study was carried out on all users who filled in the Allergy Diary from January 1, 2016 to August 1, 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach. Results: 12,143 users were registered. 6,949 users reported at least one VAS data recording. Among them, 1,887 users reported ≥ 7 VAS data. 1,195 subjects were included in the analysis of adherence. 136 (11.28%) users were adherent (MPR ≥70% and PDC ≤ 1.25), 51 (4.23%) were partly adherent (MPR ≥70% and PDC =1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non‐adherent to medications (MPR<70%). Of those, the largest group was non‐adherent to medications and the time interval was increased in 442 (36.68%) users. Conclusion and clinical relevance: Adherence to treatment is low. The relative efficacy of continuous versus on‐demand treatment for AR symptoms is still a matter of debate.This study shows an approach for measuring retrospective adherence based on a mobile app. This represent a novel approach also for analyzing medication taking behavior in a real‐world setting.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationMenditto, E., Costa, E., Midão, L., Bosnic-Anticevich, S., Novellino, E., Bialek, S., Briedis, V., Mair, A., Rajabian-Soderlund, R., Arnavielhe, S., Bedbrook, A., Czarlewski, W., Annesi-Maesano, I., Anto, J. M., Devillier, P., De Vries, G., Keil, T., Sheikh, A., Orlando, V., Larenas-Linnemann, D., Cecchi, L., De Feo, G., Illario, M., Stellato, C., Fonseca, J., Malva, J., Morais-Almeida, M., Pereira, A. M., Todo-Bom, A., Kvedariene, V., Valiulis, A., Bergmann, K. C., Klimek, L., Mösges, R., Pfaar, O., Zuberbier, T., Cardona, V., Mullol, J., Papadopoulos, N. G., Prokopakis, E. P., Bewick, M., Ryan, D., Roller-Wirnsberger, R. E., Tomazic, P. V., Cruz, A. A., Kuna, P., Samolinski, B., Fokkens, W. J., Reitsma, S., Bosse, I., Fontaine, J. F., Laune, D., Haahtela, T., Toppila-Salmi, S., Bachert, C., Hellings, P. W., Melén, E., Wickman, M., Bindslev-Jensen, C., Eller, E., O'Hehir, R. E., Cingi, C., Gemicioglu, B., Kalayci, O., Ivancevich, J. C., Bousquet, J. and the MASK group (2018) 'Adherence to treatment in allergic rhinitis using mobile technology. The MASK study', Clinical and Experimental Allergy. doi:10.1111/cea.13333en
dc.identifier.doi10.1111/cea.13333
dc.identifier.issn0954-7894
dc.identifier.issn1365-2222
dc.identifier.journaltitleClinical and Experimental Allergyen
dc.identifier.urihttps://hdl.handle.net/10468/7273
dc.language.isoenen
dc.publisherJohn Wiley & Sons, Inc.en
dc.relation.urihttps://onlinelibrary.wiley.com/doi/abs/10.1111/cea.13333
dc.rights© 2018, John Wiley & Sons, Inc. This is the peer reviewed version of the following article: Menditto, E., Costa, E., Midão, L., Bosnic-Anticevich, S., Novellino, E., Bialek, S., Briedis, V., Mair, A., Rajabian-Soderlund, R., Arnavielhe, S., Bedbrook, A., Czarlewski, W., Annesi-Maesano, I., Anto, J. M., Devillier, P., De Vries, G., Keil, T., Sheikh, A., Orlando, V., Larenas-Linnemann, D., Cecchi, L., De Feo, G., Illario, M., Stellato, C., Fonseca, J., Malva, J., Morais-Almeida, M., Pereira, A. M., Todo-Bom, A., Kvedariene, V., Valiulis, A., Bergmann, K. C., Klimek, L., Mösges, R., Pfaar, O., Zuberbier, T., Cardona, V., Mullol, J., Papadopoulos, N. G., Prokopakis, E. P., Bewick, M., Ryan, D., Roller-Wirnsberger, R. E., Tomazic, P. V., Cruz, A. A., Kuna, P., Samolinski, B., Fokkens, W. J., Reitsma, S., Bosse, I., Fontaine, J. F., Laune, D., Haahtela, T., Toppila-Salmi, S., Bachert, C., Hellings, P. W., Melén, E., Wickman, M., Bindslev-Jensen, C., Eller, E., O'Hehir, R. E., Cingi, C., Gemicioglu, B., Kalayci, O., Ivancevich, J. C., Bousquet, J. and the MASK group (2018) 'Adherence to treatment in allergic rhinitis using mobile technology. The MASK study', Clinical and Experimental Allergy. doi:10.1111/cea.13333, which has been published in final form at https://doi.org/10.1111/cea.13333. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.en
dc.subjectmHealthen
dc.subjectMobile technologyen
dc.subjectAdherenceen
dc.subjectRhinitisen
dc.subjectTreatmenten
dc.subjectObservational studyen
dc.titleAdherence to treatment in allergic rhinitis using mobile technology. The MASK Studyen
dc.typeArticle (peer-reviewed)en
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