Incidence of surgical site infection following caesarean section: a systematic review and meta-analysis protocol
| dc.contributor.author | Saeed, Khalid B. M. | |
| dc.contributor.author | Greene, Richard A. | |
| dc.contributor.author | Corcoran, Paul | |
| dc.contributor.author | O'Neill, Sinéad M. | |
| dc.contributor.funder | University College Cork | en |
| dc.date.accessioned | 2017-01-23T14:57:24Z | |
| dc.date.available | 2017-01-23T14:57:24Z | |
| dc.date.issued | 2017-01-01 | |
| dc.date.updated | 2017-01-23T14:47:39Z | |
| dc.description.abstract | Introduction: Caesarean section (CS) rates have increased globally during the past three decades. Surgical site infection (SSI) following CS is a common cause of morbidity with reported rates of 3 -15%. SSI represents a substantial burden to the health system including increased length of hospitalisation and costs of postdischarge care. The definition of SSI varies with the postoperative follow-up period among different health systems, resulting in differences in the reporting of SSI incidence. We propose to conduct the first systematic review and meta-analysis to determine the pooled estimate for the overall incidence of SSI following CS. Methods and analysis: We will perform a comprehensive search to identify all potentially relevant published studies on the incidence of SSI following CS reported from 1992 in the English language. Electronic databases including PubMed, CINAHL, EMBASE and Scopus will be searched using a detailed search strategy. Following study selection, full-text paper retrieval, data extraction and synthesis, we will appraise study quality and risk of bias and assess heterogeneity. Incidence data will be combined where feasible in a meta-analysis using Stata software and fixed-effects or random-effects models as appropriate. This systematic review will be reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Ethics and dissemination: Ethical approval is not required as this review will use published data. The review will evaluate the overall incidence of SSI following CS and will provide the first quantitative estimate of the magnitude of SSI. It will serve as a benchmark for future studies, identify research gaps and remaining challenges, and emphasise the need for appropriate prevention and control measures for SSI post-CS. A manuscript reporting the results of the systematic review and meta-analysis will be submitted to a peer-reviewed journal and presented at scientific conferences. Trial registration number CRD42015024426. | en |
| dc.description.sponsorship | University College Cork (Department of Obstetrics and Gynaecology) | en |
| dc.description.status | Peer reviewed | en |
| dc.description.version | Published Version | en |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.citation | Saeed, K. B. M., Greene, R. A., Corcoran, P. and O'Neill, S. M. (2017) 'Incidence of surgical site infection following caesarean section: a systematic review and meta-analysis protocol', BMJ Open, 7(1). doi:10.1136/bmjopen-2016-013037 | en |
| dc.identifier.doi | 10.1136/bmjopen-2016-013037 | |
| dc.identifier.endpage | e013037-5 | en |
| dc.identifier.issn | 2044-6055 | |
| dc.identifier.issued | 1 | en |
| dc.identifier.journaltitle | Bmj Open | en |
| dc.identifier.startpage | e013037-1 | en |
| dc.identifier.uri | https://hdl.handle.net/10468/3503 | |
| dc.identifier.volume | 7 | en |
| dc.language.iso | en | en |
| dc.publisher | BMJ Publishing Group | en |
| dc.rights | © 2017, The Authors. Published by the BMJ Publishing Group Limited. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ | en |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | en |
| dc.subject | Caesarean section rates | en |
| dc.subject | Surgical site infection (SSI) | en |
| dc.subject | SSI incidence | en |
| dc.subject | Post-CS surgical site infection | en |
| dc.title | Incidence of surgical site infection following caesarean section: a systematic review and meta-analysis protocol | en |
| dc.type | Article (peer-reviewed) | en |
