Synthesis & retention mechanisms of novel mixed mode stationary phase for detection of specific polar low molecular weight biological samples

Simple item page
dc.check.embargoformatNot applicableen
dc.check.infoNo embargo requireden
dc.check.opt-outNoen
dc.check.reasonNo embargo requireden
dc.check.typeNo Embargo Required
dc.contributor.advisorGlennon, Jeremy D.en
dc.contributor.authorBrowne, Damian
dc.date.accessioned2016-07-14T08:36:36Z
dc.date.available2016-07-14T08:36:36Z
dc.date.issued2013
dc.date.submitted2013
dc.description.abstractThe thesis primarily reports the synthesis, characterization and application of novel mixed mode stationary phases for Hydrophilic Interaction Liquid Chromatography (HILIC). HILIC is a rapidly emerging chromatographic mode that is finding great applicability in the analysis of polar organic molecules. In addition, there is a chapter on the analysis of Bisphenol A and related species using capillary electrophoresis (CE) coupled with boron-doped diamond electrodes for electrochemical detection. The synthesis and characterization of the novel mixed mode stationary phases prepared in this work is an important contribution to the field as the materials prepared exhibited better performance than similar materials obtained commercially. In addition a more thorough characterization of the materials (e.g.,thermogravimetric analysis, various NMR modes, elemental analysis, etc.) and resulting columns (e.g., H) than is typically encountered. The application of these new materials to the analysis of sugars using evaporative light scattering is also novel. In CE studies, electrochemical detection is sufficiently rare that the work is also novel.en
dc.description.statusNot peer revieweden
dc.description.versionAccepted Version
dc.format.mimetypeapplication/pdfen
dc.identifier.citationBrowne, D. 2013. Synthesis & retention mechanisms of novel mixed mode stationary phase for detection of specific polar low molecular weight biological samples. PhD Thesis, University College Cork.en
dc.identifier.endpage257en
dc.identifier.urihttps://hdl.handle.net/10468/2873
dc.language.isoenen
dc.publisherUniversity College Corken
dc.rights© 2013, Damian Browne.en
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/en
dc.subjectChromatographyen
dc.subjectStationary phaseen
dc.subjectZwitterionicen
dc.thesis.opt-outfalse
dc.titleSynthesis & retention mechanisms of novel mixed mode stationary phase for detection of specific polar low molecular weight biological samplesen
dc.typeDoctoral thesisen
dc.type.qualificationlevelDoctoralen
dc.type.qualificationnamePhD (Science)en
ucc.workflow.supervisorj.glennon@ucc.ie
Files
Original bundle
Now showing 1 - 2 of 2
Thumbnail Image
Name:
Abstract_Damian Browne_PhD.pdf
Size:
81.13 KB
Format:
Adobe Portable Document Format
Description:
Abstract
Thumbnail Image
Name:
Thesis_final.pdf
Size:
4.44 MB
Format:
Adobe Portable Document Format
Description:
Full Text E-thesis
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
5.62 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Doctoral Theses
Chemistry - Doctoral Theses
College of Science, Engineering and Food Science - Doctoral Theses