Healthcare Professionals’ Perspectives on Barriers and Facilitators to Medication Adherence Post Myocardial Infarction: A Qualitative Study Using the Theoretical Domains Framework

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dc.contributor.authorEl-Komy, Fatma
dc.contributor.authorO’Driscoll, Michelle
dc.contributor.authorByrne, Stephen
dc.contributor.authorBermingham, Margaret
dc.contributor.authorSahm, Laura J.
dc.date.accessioned2026-02-18T16:00:02Z
dc.date.available2026-02-18T16:00:02Z
dc.date.issued2026-02-02
dc.description.abstractMedication adherence following myocardial infarction (MI) is essential for effective secondary prevention, yet adherence rates remain suboptimal. Healthcare professionals (HCPs) are central to promoting adherence through clinical decision-making, patient education, and ongoing behavioural support. Understanding how HCPs perceive and experience the factors’ influencing adherence is key to developing effective, context-specific interventions. This study explored HCPs’ perspectives on medication adherence post-MI and identified behavioural determinants influencing medication management across the care pathway. A qualitative descriptive study was conducted using semi-structured interviews with HCPs in the southwest of Ireland. Participants included hospital pharmacists, community pharmacists, general practitioners (GPs), cardiologists, and nurses, recruited through purposive, convenience, and snowball sampling. Interviews were recorded, transcribed verbatim, and analysed using directed content analysis guided by the Theoretical Domains Framework (TDF). Twelve HCPs (eight female) were interviewed between December 2024 and May 2025, including four pharmacists, two GPs, three cardiologists and three nurses. Interviews lasted 30–50 min (mean 41 min). Analysis identified 15 facilitators, 13 barriers, and 7 dual-role determinants across 10 TDF domains. Novel contributions include demonstrating how HCPs’ real-world experiences contextualise adherence issues in the distinct post-MI setting characterised by abrupt care transitions, polypharmacy, and emotional vulnerability and identifying where HCPs feel most constrained and where their expertise could directly inform targeted intervention design. HCPs’ insights reveal complex, context-specific behavioural determinants influencing post-MI medication adherence and highlight the need for multidisciplinary, tailored, and system-level solutions. Enhancing collaboration, supporting patient-centred communication, and addressing resource barriers could empower HCPs to deliver more effective, personalised adherence support and inform the development of targeted intervention strategies.en
dc.description.versionPublished Version
dc.format.extent19
dc.format.mimetypeapplication/pdfen
dc.identifier.articleid23
dc.identifier.authororcidEl-Komy, Fatma
dc.identifier.authororcidO’Driscoll, Michelle§0000-0001-5466-4214
dc.identifier.authororcidByrne, Stephen§0000-0003-3141-7004
dc.identifier.authororcidBermingham, Margaret§0000-0002-8692-1569
dc.identifier.authororcidSahm, Laura J.§0000-0002-7496-9477
dc.identifier.citationEl-Komy, F, O’Driscoll, M, Byrne, S, Bermingham, M & Sahm, L J 2026, 'Healthcare Professionals’ Perspectives on Barriers and Facilitators to Medication Adherence Post Myocardial Infarction: A Qualitative Study Using the Theoretical Domains Framework', Pharmacy, vol. 14, no. 1, 23. https://doi.org/10.3390/pharmacy14010023
dc.identifier.doi10.3390/pharmacy14010023
dc.identifier.issn2226-4787
dc.identifier.issued1
dc.identifier.journaltitlePharmacy
dc.identifier.otherORCID: /0000-0002-8692-1569/work/204422456
dc.identifier.otherORCID: /0000-0003-3141-7004/work/206113776
dc.identifier.otherORCID: /0000-0002-7496-9477/work/206114289
dc.identifier.otherORCID: /0000-0001-5466-4214/work/216579439
dc.identifier.urihttps://hdl.handle.net/10468/18549
dc.identifier.volume14
dc.language.isoen
dc.relation.urihttps://doi.org/10.3390/pharmacy14010023
dc.rights© 2026, the Authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
dc.rights.accessrightsopen access
dc.statusPeer reviewed
dc.subjectMedication adherence
dc.subjectMyocardial infarction
dc.subjectHealthcare professionals
dc.subjectHealth knowledge
dc.subjectPatient education
dc.subjectBarriers
dc.subjectFacilitators
dc.subject[Pharmacy]
dc.titleHealthcare Professionals’ Perspectives on Barriers and Facilitators to Medication Adherence Post Myocardial Infarction: A Qualitative Study Using the Theoretical Domains Frameworken
dc.typeArticle (peer-reviewed)
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