Copper-nanostructure-modified laser-scribed electrodes based on graphitic carbon for electrochemical detection of dopamine and glucose
Juska, Vuslat B.
John Wiley & Sons, Inc.
Background: Carbon-based nanostructures have been attracting major interest in many research fields, including chemical and biological sensing, because of their unique structural dimensions and excellent physical, chemical and mechanical properties. A recently developed laser scribing approach allows design and fabrication of flexible, graphitic carbon-based substrates for (bio-)electrochemical applications, as it provides highly robust and low-cost sensing platforms. Results: Here we demonstrate the fabrication of a highly reproducible laser-scribed graphitic electrode (LSE) on a polyimide (Kapton) film using a simple, do-it-yourself laser engraving system equipped with a 405 nm wavelength laser. Copper nanostructures were deposited onto an electrode surface via the electrodeposition process. The developed three-dimensional graphitic electrodes modified by nano copper/copper oxide species (LSE-Cu) were used for the detection of dopamine and glucose. Electrochemical studies of LSE-Cu showed that in the presence of nano-copper there is an apparent shift of the oxidation peaks of dopamine and ascorbic acid, allowing determination of dopamine without an interference effect, with an excellent sensitivity of 1321.54 mu A L mmol(-1) cm(-2). Furthermore, the LSE-Cu sensor exhibited highly satisfying analytical performance towards glucose electro-oxidation, with a reproducibility of 5.47% (RSD %). Conclusion: We have demonstrated a simple design, fabrication and passivation route for the preparation of LSEs performing as biosensors. Such a cost-effective and design-flexible system is highly suitable for developing a biosensing platform towards various target analytes and further miniaturization of the electrode.
Laser-scribed electrode , Graphitic carbon , Graphene , Dopamine detection , Glucose detection
Juska, V. B. and Juska, G. (2020) 'Copper-nanostructure-modified laser-scribed electrodes based on graphitic carbon for electrochemical detection of dopamine and glucose', Journal of Chemical Technology and Biotechnology, 96(4), pp. 1086-1095. doi: 10.1002/jctb.6620
© 2020, Society of Chemical Industry. Published by John Wiley & Sons Ltd. This is the peer reviewed version of the following item: Juska, V. B. and Juska, G. (2020) 'Copper-nanostructure-modified laser-scribed electrodes based on graphitic carbon for electrochemical detection of dopamine and glucose', Journal of Chemical Technology and Biotechnology, 96(4), pp. 1086-1095, doi: 10.1002/jctb.6620, which has been published in final form at: https://doi.org/10.1002/jctb.6620 This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.