Synthesis of enantioenriched sulfoxides

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dc.contributor.authorO'Mahony, Graham E.
dc.contributor.authorKelly, Padraig
dc.contributor.authorLawrence, Simon E.
dc.contributor.authorMaguire, Anita R.
dc.date.accessioned2012-05-29T15:50:00Z
dc.date.available2012-05-29T15:50:00Z
dc.date.copyright2011-03-12
dc.date.issued2011-03-12
dc.description.abstractThis review discusses strategies for the asymmetric synthesis of sulfoxides, compounds with many applications in stereoselective synthesis and in some cases with pharmaceutical application. The review describes asymmetric oxidation, including metal catalyzed and non-metal and biological oxidation processes, in addition to synthetic approaches via nucleophilic substitution of appropriately substituted precursors. Kinetic resolution in oxidation of sulfoxides to the analogous sulfones is also discussed; in certain instances, access to enantioenriched sulfoxides can be achieved via a combination of asymmetric sulfide oxidation and complementary kinetic resolution in sulfoxide oxidation.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationO'MAHONY, G.E., KELLY, P., LAWRENCE, S.E., MAGUIRE, A.R., 2011. Synthesis of enantioenriched sulfoxides. ARKIVOC, 1-110.en
dc.identifier.endpage110en
dc.identifier.issn1551-7012
dc.identifier.issuedien
dc.identifier.journaltitleArkivocen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/597
dc.identifier.volume2011en
dc.language.isoenen
dc.publisherARKAT USAen
dc.relation.urihttp://www.arkat-usa.org/get-file/38487/
dc.relation.urihttp://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/2011/1/
dc.rights©ARKAT-USA, Inc.en
dc.subjectSulfide oxidationen
dc.subjectSulfoxidesen
dc.subjectAsymmetric synthesisen
dc.subjectEnantioselective synthesisen
dc.subjectKinetic resolutionen
dc.titleSynthesis of enantioenriched sulfoxidesen
dc.typeReviewen
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