The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

dc.contributor.authorThompson, Julie D.
dc.contributor.authorGibson, Toby J.
dc.contributor.authorPlewniak, Frederica
dc.contributor.authorJeanmougin, Francois
dc.contributor.authorHiggins, Desmond G.
dc.contributor.funderInstitut National de la Santé et de la Recherche Médicale
dc.contributor.funderCentre National de la Recherche Scientifique
dc.contributor.funderMinistère de l'Enseignement Supérieur, de la Recherche, de la Science et de la Technologie
dc.contributor.funderEuropean Bioinformatics Institute
dc.date.accessioned2017-11-14T13:24:33Z
dc.date.available2017-11-14T13:24:33Z
dc.date.issued1997
dc.description.abstractCLUSTAL X is a new windows interface for the widely-used progressive multiple sequence alignment program CLUSTAL W, The new system is easy to use, providing an integrated system for performing multiple sequence and profile alignments and analysing the results, CLUSTAL X displays the sequence alignment in a window on the screen, A versatile sequence colouring scheme allows the user to highlight conserved features in the alignment, Pull-down menus provide all the options required for traditional multiple sequence and profile alignment, New features include: the ability to cut-and-paste sequences to change the order of the alignment, selection of a subset of the sequences to be realigned, and selection of a sub-range of the alignment to be realigned and inserted back into the original alignment, Alignment quality analysis can be performed and low-scoring segments or exceptional residues can be highlighted, Quality analysis and realignment of selected residue ranges provide the user with a powerful tool to improve and refine difficult alignments and to trap errors in input sequences, CLUSTAL X has been compiled on SUN Solaris, IRIX5.3 on Silicon Graphics, Digital UNIX on DECstations, Microsoft Windows (32 bit) for PCs, Linux ELF for x86 PCs, and Macintosh PowerMac.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationThompson, J. D., Gibson, T. J., Plewniak, F., Jeanmougin, F. and Higgins, D. G. (1997) 'The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools', Nucleic Acids Research, 25(24), pp. 4876-4882. doi: 10.1093/nar/25.24.4876en
dc.identifier.doi10.1093/nar/25.24.4876
dc.identifier.endpage4882
dc.identifier.issn0305-1048
dc.identifier.issued24
dc.identifier.journaltitleNucleic Acids Researchen
dc.identifier.startpage4876
dc.identifier.urihttps://hdl.handle.net/10468/5038
dc.identifier.volume25
dc.language.isoenen
dc.publisherOxford University Pressen
dc.relation.urihttps://academic.oup.com/nar/article-lookup/doi/10.1093/nar/25.24.4876
dc.rights© 1997, Oxford University Pressen
dc.subjectProtein sequencesen
dc.subjectSecondary structureen
dc.subjectSensitivityen
dc.subjectWeightsen
dc.subjectProfileen
dc.titleThe CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis toolsen
dc.typeArticle (peer-reviewed)en
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