Uterine artery embolisation of fibroids and the phenomenon of post-embolisation syndrome: A systematic review

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dc.contributor.authorWaldron, Michael G.en
dc.contributor.authorKassamani, Yara W.en
dc.contributor.authorO’Mahony, Alexander T.en
dc.contributor.authorO’Mahony, Siobhain M.en
dc.contributor.authorO'Sullivan, Orfhlaith E.en
dc.contributor.authorPower, Stephen P.en
dc.contributor.authorSpence, Liamen
dc.contributor.authorMaher, Michael M.en
dc.contributor.authorO’Connor, Owen J.en
dc.contributor.authorBuckley, Maria M.en
dc.date.accessioned2025-03-04T10:28:07Z
dc.date.available2025-03-04T10:28:07Z
dc.date.issued2022en
dc.description.abstractPost-embolisation syndrome (PES) is a prevalent complication that occurs in patients following uterine artery embolisation (UAE) for the treatment of uterine fibroids. The aetiology of PES remains incompletely understood, although postulated to result secondary to tissue infarction resulting in release of inflammatory mediators. We followed PRISMA guidelines and performed a systematic review of studies of PES following UAE from inception to October 2022. Our published protocol was prospectively registered. Our search yielded 54 results. We reviewed 22 full texts, and nine articles were included. Observational studies comprised 6/9 relevant studies, with 5/9 retrospective design. The rate of PES was documented in 5/8 studies (excluding case report) with a reported incidence ranging from 4–34.6%. Five of the nine studies studies postulated that the aetiological basis of PES is inflammatory related. Further research is necessary to advance our understanding of PES to define the biological basis of the syndrome with more certainty and gain a consensus on peri-procedure management to reduce incidence and improve patient outcomes. © 2022 by the authors.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleid2916en
dc.identifier.citationWaldron, M. G., Kassamani, Y. W., O’Mahony, A. T., O’Mahony, S. M., O’Sullivan, O. E., Power, S. P., Spence, L., Maher, M. M., O’Connor, O. J. and Buckley, M. M. (2022) 'Uterine artery embolisation of fibroids and the phenomenon of post-embolisation syndrome: a systematic review', Diagnostics, 12(12), p.2916. https://doi.org/10.3390/diagnostics12122916en
dc.identifier.doihttps://doi.org/10.3390/diagnostics12122916en
dc.identifier.issn20754418en
dc.identifier.issued12
dc.identifier.journaltitleDiagnosticsen
dc.identifier.urihttps://hdl.handle.net/10468/17144
dc.identifier.volume12
dc.language.isoenen
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)en
dc.rights© 2022, the Author(s). This work is licensed under a Creative Commons Attribution 4.0 International License.en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectFibroidsen
dc.subjectInflammationen
dc.subjectPost-embolisation syndromeen
dc.subjectUterine artery embolizationen
dc.titleUterine artery embolisation of fibroids and the phenomenon of post-embolisation syndrome: A systematic reviewen
dc.typeArticle (peer reviewed)en
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