Microneedle electrodes: materials, fabrication methods, and electrophysiological signal monitoring-narrative review

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dc.check.date2026-02-25
dc.contributor.authorSingh, Om Prakashen
dc.contributor.authorEl-Badawy, Ismail M.en
dc.contributor.authorSundaram, Sornambikaien
dc.contributor.authorO'Mahony, Conoren
dc.contributor.funderHigher Education Authorityen
dc.contributor.funderScience Foundation Irelanden
dc.contributor.funderEuropean Regional Development Funden
dc.date.accessioned2025-03-20T15:58:16Z
dc.date.available2025-03-20T15:58:16Z
dc.date.issued2025en
dc.description.abstractFlexible, microneedle-based electrodes offer an innovative solution for high-quality physiological signal monitoring, reducing the need for complex algorithms and hardware, thus streamlining health assessments, and enabling earlier disease detection. These electrodes are particularly promising for improving patient outcomes by providing more accurate, reliable, and long-term electrophysiological data, but their clinical adoption is hindered by the limited availability of large-scale population testing. This review examines the key advantages of flexible microneedle electrodes, including their ability to conform to the skin, enhance skin-electrode contact, reduce discomfort, and deliver superior signal fidelity. The mechanical and electrical properties of these electrodes are thoroughly explored, focusing on critical aspects like fracture force, skin penetration efficiency, and impedance measurements. Their applications in capturing electrophysiological signals such as ECG, EMG, and EEG are also highlighted, demonstrating their potential in clinical scenarios. Finally, the review outlines future research directions, emphasizing the importance of further studies to enhance the clinical and consumer use of flexible microneedle electrodes in medical diagnostics.en
dc.description.sponsorshipHigher Education Authority (Disruptive Technologies Innovation Fund (DT2018 0291-A, HOLISTICS))en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleid9en
dc.identifier.citationSingh, O.P., El-Badawy, I.M., Sundaram, S. and O’Mahony, C. (2025) ‘Microneedle electrodes: materials, fabrication methods, and electrophysiological signal monitoring-narrative review’, Biomedical Microdevices, 27(1), 9. https://doi.org/10.1007/s10544-024-00732-zen
dc.identifier.doihttps://doi.org/10.1007/s10544-024-00732-zen
dc.identifier.endpage33en
dc.identifier.issued1en
dc.identifier.journaltitleBiomedical Microdevicesen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/17192
dc.identifier.volume27en
dc.language.isoenen
dc.publisherSpringer Natureen
dc.relation.projectinfo:eu-repo/grantAgreement/AKA//343670/FI/Program director - Disruptive Technologies and Changing Institutions/en
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Maternity/Adoptive Leave Allowance/12/RC/2289-P2s/IE/INSIGHT Phase 2/en
dc.rights© the Authors, under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2025en
dc.subjectMicroneedleen
dc.subjectSensoren
dc.subjectDeviceen
dc.subject3-D printingen
dc.subjectDiagnosticen
dc.titleMicroneedle electrodes: materials, fabrication methods, and electrophysiological signal monitoring-narrative reviewen
dc.typeArticle (peer-reviewed)en
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