Analgesic efficacy of a single dose intrathecal morphine in patients undergoing robot-assisted laparoscopic prostatectomy (RALP)

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dc.contributor.authorWolff, Erikaen
dc.contributor.authorIohom, Gabriellaen
dc.contributor.editorMehta, Shobhaen
dc.contributor.editorCronin, Pádraigen
dc.date.accessioned2025-10-28T13:54:56Z
dc.date.available2025-10-28T13:54:56Z
dc.date.issued2025en
dc.description.abstractBackground: The World Federation of Societies of Anaesthesiologists has established guidelines for anaesthesia in laparoscopic surgery, but detailed protocols for perioperative pain management in Robot-Assisted Laparoscopic Prostatectomy (RALP) are lacking (1). This study evaluated the analgesic efficacy of a single intrathecal morphine (ITM) dose in RALP. Methods: Following Ethics Committee approval, a retrospective chart review of 79 patient charts that underwent RALP procedures between 01/01/2021 and 31/05/2023 was conducted. One patient was excluded due to regular codeine use. Patients were divided into ITM (n=18) and non-ITM (NITM, n=60). Outcomes included recovery room pain scores, opioid requirements, time to first opioid request, 24-hour postoperative opioid consumption, opioid-related side effects, and anti-emetic usage. Data was analyzed using SPSS, with P<0.05 considered significant. Results: The median [IQR] ITM dose was 200 [50] micrograms. Pain scores in the RR and 24-hour opioid consumption were similar between groups. However, the ITM group had a longer time to first opioid request compared to the NITM group (16.64 [22.9] vs. 1.32 [7.78] hours, P=0.05). Morphine-related side effects were more frequent in the ITM group (16.7% vs. 0%, P<0.001), as was anti-emetic usage (55.6% vs. 15.3%, P=0.001). Conclusion: In conclusion, a single dose of intrathecal morphine delayed the time to first opioid request in RALP patients but was associated with higher rates of side effects and anti-emetic use. These findings highlight the need to weigh the benefits of analgesia against the potential for increased adverse effects in patients undergoing RALP.en
dc.description.statusNot peer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationWolff, E. and Iohom, G. (2025)'Analgesic efficacy of a single dose intrathecal morphine in patients undergoing robot-assisted laparoscopic prostatectomy (RALP)', UCC Student Medical Journal, 5, p.54. https://doi.org/10.33178/SMJ.2025.1.8en
dc.identifier.doi10.33178/SMJ.2025.1.8en
dc.identifier.endpage54en
dc.identifier.issn2737-7237
dc.identifier.journalabbrevUCC SMJ
dc.identifier.journaltitleUCC Student Medical Journalen
dc.identifier.startpage54en
dc.identifier.urihttps://hdl.handle.net/10468/18085
dc.identifier.volume5
dc.language.isoenen
dc.publisherUCC Medical Research and Technology Societyen
dc.rights© 2025, the Author(s). This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.en
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0
dc.sourceBatch uploaden
dc.subjectSpinal anaesthesiaen
dc.subjectRobot-assisted laparoscopic prostatectomyen
dc.subjectPain managementen
dc.titleAnalgesic efficacy of a single dose intrathecal morphine in patients undergoing robot-assisted laparoscopic prostatectomy (RALP)en
dc.typeArticle (peer-reviewed)en
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