Adverse childhood experiences (ACEs) and later-life depression: perceived social support as a potential protective factor

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dc.contributor.authorCheong, E. Von
dc.contributor.authorSinnott, Carol
dc.contributor.authorDahly, Darren L.
dc.contributor.authorKearney, Patricia M.
dc.contributor.funderHealth Research Board
dc.date.accessioned2017-10-18T09:40:15Z
dc.date.available2017-10-18T09:40:15Z
dc.date.issued2017
dc.description.abstractObjective: To investigate associations between adverse childhood experiences (ACEs) and later-life depressive symptoms; and to explore whether perceived social support (PSS) moderates these. Method: We analysed baseline data from the Mitchelstown (Ireland) 2010–2011 cohort of 2047 men and women aged 50–69 years. Self-reported measures included ACEs (Centre for Disease Control ACE questionnaire), PSS (Oslo Social Support Scale) and depressive symptoms (CES-D). The primary exposure was self-report of at least one ACE. We also investigated the effects of ACE exposure by ACE scores and ACE subtypes abuse, neglect and household dysfunction. Associations between each of these exposures and depressive symptoms were estimated using logistic regression, adjusted for socio-demographic factors. We tested whether the estimated associations varied across levels of PSS (poor, moderate and strong). Results: 23.7% of participants reported at least one ACE (95% CI 21.9% to 25.6%). ACE exposures (overall, subtype or ACE scores) were associated with a higher odds of depressive symptoms, but only among individuals with poor PSS. Exposure to any ACE (vs none) was associated with almost three times the odds of depressive symptoms (adjusted OR 2.85; 95% CI 1.64 to 4.95) among individuals reporting poor PSS, while among those reporting moderate and strong PSS, the adjusted ORs were 2.21 (95% CI 1.52 to 3.22) and 1.39 (95% CI 0.85 to 2.29), respectively. This pattern of results was similar when exposures were based on ACE subtype and ACE scores, though the interaction was clearly strongest among those reporting abuse. Conclusions: ACEs are common among older adults in Ireland and are associated with higher odds of later-life depressive symptoms, particularly among those with poor PSS. Interventions that enhance social support, or possibly perceptions of social support, may help reduce the burden of depression in older populations with ACE exposure, particularly in those reporting abuse.en
dc.description.sponsorshipHealth Research Board (HRC/2007/13).en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleide013228
dc.identifier.citationCheong, E. V., Sinnott, C., Dahly, D. and Kearney, P. M. (2017) 'Adverse childhood experiences (ACEs) and later-life depression: perceived social support as a potential protective factor', BMJ Open, 7(9), e013228 (12pp). doi: 10.1136/bmjopen-2016-013228en
dc.identifier.doi10.1136/bmjopen-2016-013228
dc.identifier.endpage12
dc.identifier.issn2044-6055
dc.identifier.issued9
dc.identifier.journaltitleBMJ Openen
dc.identifier.startpage1
dc.identifier.urihttps://hdl.handle.net/10468/4897
dc.identifier.volume7
dc.language.isoenen
dc.publisherBMJ Publishing Groupen
dc.relation.urihttp://bmjopen.bmj.com/content/7/9/e013228
dc.rights© 2017, Article authors or their employer unless otherwise stated in the text of the Article. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/en
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.subjectAdverse childhood experiencesen
dc.subjectACEen
dc.subjectPSSen
dc.subjectDepressionen
dc.titleAdverse childhood experiences (ACEs) and later-life depression: perceived social support as a potential protective factoren
dc.typeArticle (peer-reviewed)en
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