Laser-induced graphene-based potentiometric pH and nonenzymatic uric acid sensors for urine analysis on baby diaper

dc.contributor.authorRasel, Md
dc.contributor.authorTeixeira, Sofia Rodrigues
dc.contributor.authorIslam, Jahidul
dc.contributor.authorHamidi, Hassan
dc.contributor.authorQuinn, Aidan J.
dc.contributor.authorIacopino, Daniela
dc.contributor.funderTaighde Éireann - Research Ireland
dc.contributor.funderHorizon Europe
dc.contributor.funderEuropean Regional Development Fund
dc.date.accessioned2026-05-26T11:50:04Z
dc.date.available2026-05-26T11:50:04Z
dc.date.issued2026-04-23
dc.description.abstractThe fabrication of wearable sensors and their integration into real devices is an emerging demand in the field of sensor development. In this work, flexible sensors based on laser-induced graphene (LIG) were developed using a low-cost visible laser on polyimide tape for pH and uric acid monitoring in urine. A potentiometric pH sensor was fabricated by modifying the LIG surface with polyaniline, achieving a sensitivity of 56.7 ± 2.6 mV/pH across a wide pH range (4–10) with a rapid response time of <10 s. The sensor exhibited high selectivity toward proton ions and maintained stable performance for 6 weeks without the need for preconditioning or special storage conditions. In parallel, a nonenzymatic uric acid sensor based on LIG exhibited strong selectivity against common interfering species, excellent reproducibility (RSD <1%), and a sensitivity of 116.4 μAdec–1, with a limit of detection (LOD) of 35 μM (3S/N) in the concentration range of 0.05–0.6 mM in buffer solution. Both sensors maintained almost similar sensitivities in artificial urine samples, and their performance was successfully demonstrated in baby diapers using a portable potentiostat, highlighting their potential for miniaturized wearable health monitoring applications.en
dc.description.sponsorshipThis publication has emanated from research conducted with the financial support of the Research Ireland under the European Regional Development Fund Grant Number 13/RC/2077-P2 (CONNECT) and Horizon Europe projects GreenArt (101060941) and Herit4ages (101123175).
dc.description.versionPublished Version
dc.format.extent10
dc.format.mimetypeapplication/pdfen
dc.identifier.authororcidRasel, Md
dc.identifier.authororcidTeixeira, Sofia Rodrigues
dc.identifier.authororcidIslam, Jahidul§0000-0002-2190-7870
dc.identifier.authororcidHamidi, Hassan§0000-0002-7775-8536
dc.identifier.authororcidQuinn, Aidan J.§0000-0003-4021-9990
dc.identifier.authororcidIacopino, Daniela§0000-0003-2301-9401
dc.identifier.citationRasel, M, Teixeira, S R, Islam, J, Hamidi, H, Quinn, A J & Iacopino, D 2026, 'Laser-induced graphene-based potentiometric pH and nonenzymatic uric acid sensors for urine analysis on baby diaper', ACS Omega, vol. 11, no. 17, pp. 25139-25148. https://doi.org/10.1021/acsomega.5c11146
dc.identifier.doi10.1021/acsomega.5c11146
dc.identifier.endpage25148
dc.identifier.issn2470-1343
dc.identifier.issued17
dc.identifier.journaltitleACS Omega
dc.identifier.otherRIS: urn:97C89DAE9C1CA294ADCD893E9918EC2C
dc.identifier.otherORCID: /0000-0003-2301-9401/work/215853251
dc.identifier.otherORCID: /0000-0002-7775-8536/work/215853286
dc.identifier.otherORCID: /0000-0002-2190-7870/work/215854071
dc.identifier.startpage25139
dc.identifier.urihttps://hdl.handle.net/10468/18891
dc.identifier.volume11
dc.language.isoen
dc.publisherAmerican Chemical Society
dc.relation.urihttps://www.scopus.com/pages/publications/105037854898
dc.relation.urihttps://www.scopus.com/pages/publications/105037854898?origin=resultslist
dc.rights© 2026, the Authors. .Published by American Chemical Society.
dc.rights.accessrightsopen access
dc.rights.licensenameAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.statusPeer reviewed
dc.subjectBaby diaper
dc.subjectLaser-induced graphene-based potentiometric pH and nonenzymatic uric acid sensors
dc.subjectUrine analysis
dc.subject[TyndallMicroNano]
dc.titleLaser-induced graphene-based potentiometric pH and nonenzymatic uric acid sensors for urine analysis on baby diaperen
dc.typeArticle (peer-reviewed)
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