The incidence of postoperative venous thrombosis among patients with ulcerative colitis

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dc.contributor.authorO'Connor, Owen J.
dc.contributor.authorCahill, Ronan A.
dc.contributor.authorKirwan, William O.
dc.contributor.authorRedmond, H. Paul
dc.date.accessioned2016-07-13T15:47:22Z
dc.date.available2016-07-13T15:47:22Z
dc.date.issued2005-07
dc.date.updated2012-09-26T13:32:38Z
dc.description.abstractBackground: Patients with Ulcerative Colitis (UC) have inherent prothrombotic tendencies. It is unknown whether this necessitates the use of additional perioperative anti-thrombotic prophylaxis when such patients require major surgery. Methods: The postoperative courses of 79 patients with UC undergoing 180 major abdominal and pelvic operations were examined for clinical and radiological evidence of venous thrombosis. Eighteen patients with Familial Adenomatous Polyposis (FAP) having surgery (35 operations) of similar magnitude were also studied. Standard anti-thrombosis prophylaxis was utilised in all patients. Results: Nine patients with UC were clinically suspected of developing postoperative venous thrombosis, but only three (3.8%) had their diagnosis confirmed radiologically (all had a pulmonary embolus). Therefore, the overall postoperative thrombosis rate, on an intention to treat basis, was 1.7% (3/180). No patient with FAP developed significant venous thrombosis. Conclusion: Standard perioperative antithrombotic modalities are sufficient to maintain any potential increase in postoperative thrombotic risk at an acceptable level in patients with UC undergoing operative intervention.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationO'Connor, O. J., Cahill, R. A., Kirwan, W. O. and Redmond, H. P. (2005) 'The incidence of postoperative venous thrombosis among patients with ulcerative colitis'. Irish Journal of Medical Science, 174(3), pp. 20-22. http://dx.doi.org/10.1007/BF03169142en
dc.identifier.doi10.1007/BF03169142
dc.identifier.endpage22en
dc.identifier.issn1863-4362
dc.identifier.issn0021-1265
dc.identifier.issued3en
dc.identifier.journaltitleIrish Journal of Medical Scienceen
dc.identifier.startpage20en
dc.identifier.urihttps://hdl.handle.net/10468/2872
dc.identifier.volume174en
dc.language.isoenen
dc.publisherSpringeren
dc.rights© Springer 2005. The final publication is available at Springer via http://dx.doi.org/10.1007/BF03169142en
dc.subjectDeep vein thrombosisen
dc.subjectUlcerative colitisen
dc.subjectAnti-thrombotic prophylaxisen
dc.subjectPost-operative thrombotic risken
dc.titleThe incidence of postoperative venous thrombosis among patients with ulcerative colitisen
dc.typeArticle (peer-reviewed)en
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