Development of a novel single-use microneedle design platform for increased patient compliance

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dc.contributor.authorMárquez-Graña, C.
dc.contributor.authorBryan, K.
dc.contributor.authorVucen, Sonja
dc.contributor.authorO'Sullivan, Caroline
dc.contributor.funderCork Institute of Technology
dc.date.accessioned2018-09-06T10:39:34Z
dc.date.available2018-09-06T10:39:34Z
dc.date.issued2017
dc.description.abstractMicroneedles (MN) skin patches are novel medical devices in micron scale with a needle array which offers an alternative drug delivery system to conventional methods. MN patches are applied onto the skin reaching the dermal layer where the drug molecules are released at a specific rate. There is a lack of knowledge surrounding some determinant factors required to define an efficient MN application into the user skin. The aim of the project is to determine the optimum application parameters to fabricate a polymeric MN patch and to design a disposable single-use MN applicator with enhanced usability.en
dc.description.sponsorshipCIT for (RISAM funding of PhD studies)en
dc.description.sponsorshipCork Institute of Technology (RÍSAM PhD Scholarship)
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationMárquez-Graña, C., Bryan, K., Vucen, S. and O’Sullivan, C. (2017) 'Development of a novel single-use microneedle design platform for increased patient compliance', Procedia Manufacturing, 13, pp. 1352-1359. doi:10.1016/j.promfg.2017.09.114en
dc.identifier.doi10.1016/j.promfg.2017.09.114
dc.identifier.endpage1359
dc.identifier.issn2351-9789
dc.identifier.journaltitleProcedia Manufacturingen
dc.identifier.startpage1352
dc.identifier.urihttps://hdl.handle.net/10468/6722
dc.identifier.volume13
dc.language.isoenen
dc.publisherElsevier B.V.en
dc.relation.urihttps://www.sciencedirect.com/science/article/pii/S2351978917307497
dc.rights© 2017, the Authors. Published by Elsevier B.V. This article is made available under the Creative Commons Attribution-Non Commercial-No Derivs (CC BY-NC-ND) license.en
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
dc.subjectMicroneedle patchesen
dc.subjectPLGAen
dc.subjectSelf-applicatoren
dc.subjectAtomised sprayen
dc.subjectSterilizationen
dc.subjectState-of-art reviewen
dc.titleDevelopment of a novel single-use microneedle design platform for increased patient complianceen
dc.typeArticle (peer-reviewed)en
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