Ten quick tips for classifying unknown bacteriophage

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dc.contributor.authorBastiaanssen, Fabian T.S.
dc.contributor.authorHill, Colin
dc.contributor.authorShkoporov, Andrey N.
dc.contributor.funderScience Foundation Ireland (SFI)
dc.contributor.funderEuropean Research Council
dc.date.accessioned2026-07-13T12:50:02Z
dc.date.available2026-07-13T12:50:02Z
dc.date.issued2026-06-01
dc.description.abstractIn microbiome research, bacteriophages (phages) are gaining increased attention for their roles as important ecological actors, as vehicles of horizontal gene transfer, and as “phagebiotics”—potential tools for precision microbiome manipulation: phage cocktails to suppress specific pathogens/pathobionts, “virome transplants” to restore microbiome diversity and functionality, phage vectors for delivery of CRISPR-Cas for microbiome editing. Once referred to as “viral dark matter” [1,2] of the microbiome, complex populations of bacteriophages are becoming easier to sequence and identify thanks to recent advances in high throughput virome sequencing and phage bioinformatics.en
dc.description.sponsorshipScience Foundation Ireland|SFI/12/RC/2273_P2 Science Foundation Ireland|SFI/12/RC/2273 European Research Council|101001684
dc.description.versionPublished Version
dc.format.extent9
dc.format.mimetypeapplication/pdfen
dc.identifier.articleide1014403
dc.identifier.authororcidBastiaanssen, Fabian T.S.
dc.identifier.authororcidHill, Colin§0000-0002-8527-1445
dc.identifier.authororcidShkoporov, Andrey N.
dc.identifier.citationBastiaanssen, F T S, Hill, C & Shkoporov, A N 2026, 'Ten quick tips for classifying unknown bacteriophage', PLOS Computational Biology, vol. 22, no. 6, e1014403, pp. 1-9. https://doi.org/10.1371/journal.pcbi.1014403
dc.identifier.doi10.1371/journal.pcbi.1014403
dc.identifier.endpage9
dc.identifier.issn1553-734X
dc.identifier.issued6
dc.identifier.journaltitlePLOS Computational Biology
dc.identifier.otherORCID: /0000-0002-8527-1445/work/220589709
dc.identifier.startpage1
dc.identifier.urihttps://hdl.handle.net/10468/19055
dc.identifier.volume22
dc.language.isoen
dc.publisherPublic Library of Science
dc.relation.urihttps://www.scopus.com/pages/publications/105043672312
dc.rights© 2026, Bastiaanssen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.rights.accessrightsopen access
dc.rights.licensenameAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.statusPeer reviewed
dc.subjectBacteriophage
dc.subjectVirus
dc.subjectMicrobiome
dc.subject[Microbiology]
dc.subject[APCMicrobiome]
dc.titleTen quick tips for classifying unknown bacteriophageen
dc.typeArticle (peer-reviewed)
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