Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases

dc.contributor.authorBousquet, J. J.
dc.contributor.authorSchünemann, H. J.
dc.contributor.authorTogias, A.
dc.contributor.authorErhola, M.
dc.contributor.authorHellings, P. W.
dc.contributor.authorZuberbier, T.
dc.contributor.authorAgache, I.
dc.contributor.authorAnsotegui, I. J.
dc.contributor.authorAnto, J. M.
dc.contributor.authorBachert, C.
dc.contributor.authorBecker, S.
dc.contributor.authorBedolla-Barajas, M.
dc.contributor.authorBewick, M.
dc.contributor.authorBosnic-Anticevich, S.
dc.contributor.authorBosse, I.
dc.contributor.authorBoulet, L. P.
dc.contributor.authorBourrez, J. M.
dc.contributor.authorBrusselle, G.
dc.contributor.authorChavannes, N.
dc.contributor.authorCosta, E.
dc.contributor.authorCruz, A. A.
dc.contributor.authorCzarlewski, W.
dc.contributor.authorFokkens, W. J.
dc.contributor.authorFonseca, J. A.
dc.contributor.authorGaga, M.
dc.contributor.authorHaahtela, T.
dc.contributor.authorIllario, M.
dc.contributor.authorKlimek, L.
dc.contributor.authorKuna, P.
dc.contributor.authorKvedariene, V.
dc.contributor.authorLe, L. T. T.
dc.contributor.authorLarenas-Linnemann, D.
dc.contributor.authorLaune, D.
dc.contributor.authorLourenço, O. M.
dc.contributor.authorMenditto, E.
dc.contributor.authorMullol, J.
dc.contributor.authorOkamoto, Y.
dc.contributor.authorPapadopoulos, N.
dc.contributor.authorPham-Thi, N.
dc.contributor.authorPicard, R.
dc.contributor.authorPinnock, H.
dc.contributor.authorRoche, N.
dc.contributor.authorRoller-Wirnsberger, R. E.
dc.contributor.authorRolland, C.
dc.contributor.authorSamolinski, B.
dc.contributor.authorSheikh, A.
dc.contributor.authorToppila-Salmi, S.
dc.contributor.authorTsiligianni, I.
dc.contributor.authorValiulis, A.
dc.contributor.authorValovirta, E.
dc.contributor.authorVasankari, T.
dc.contributor.authorVentura, M.-T.
dc.contributor.authorWalker, S.
dc.contributor.authorWilliams, S.
dc.contributor.authorAkdis, Cezmi A.
dc.contributor.authorAnnesi-Maesano, I.
dc.contributor.authorArnavielhe, S.
dc.contributor.authorBasagana, X.
dc.contributor.authorBateman, Eric D.
dc.contributor.authorBedbrook, A.
dc.contributor.authorBennoor, K. S.
dc.contributor.authorBenveniste, S.
dc.contributor.authorBergmann, K. C.
dc.contributor.authorBialek, S.
dc.contributor.authorBillo, N.
dc.contributor.authorBindslev-Jensen, C.
dc.contributor.authorBjermer, L.
dc.contributor.authorBlain, H.
dc.contributor.authorBonini, M.
dc.contributor.authorBonniaud, P.
dc.contributor.authorBouchard, J.
dc.contributor.authorBriedis, V.
dc.contributor.authorBrightling, C. E.
dc.contributor.authorBrozek, J.
dc.contributor.authorBuhl, R.
dc.contributor.authorBuonaiuto, R.
dc.contributor.authorCanonica, G. W.
dc.contributor.authorCardona, V.
dc.contributor.authorCarriazo, A. M.
dc.contributor.authorCarr, W.
dc.contributor.authorCartier, C.
dc.contributor.authorCasale, T.
dc.contributor.authorCecchi, L.
dc.contributor.authorCepeda Sarabia, A. M.
dc.contributor.authorChkhartishvili, E.
dc.contributor.authorChu, D. K.
dc.contributor.authorCingi, C.
dc.contributor.authorColgan, E.
dc.contributor.authorde Sousa, J. C.
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dc.contributor.authorCustovic, A.
dc.contributor.authorCvetkosvki, B.
dc.contributor.authorD’Amato, G.
dc.contributor.authorda Silva, J.
dc.contributor.authorDantas, C.
dc.contributor.authorDokic, D.
dc.contributor.authorDauvilliers, Y.
dc.contributor.authorDedeu, A.
dc.contributor.authorDe Feo, G.
dc.contributor.authorDevillier, P.
dc.contributor.authorDi Capua, S.
dc.contributor.authorDykewickz, M.
dc.contributor.authorDubakiene, R.
dc.contributor.authorEbisawa, M.
dc.contributor.authorEl-Gamal, Y.
dc.contributor.authorEller, E.
dc.contributor.authorEmuzyte, R.
dc.contributor.authorFarrell, J.
dc.contributor.authorFink-Wagner, A.
dc.contributor.authorFiocchi, A.
dc.contributor.authorFontaine, J. F.
dc.contributor.authorGemicioğlu, B.
dc.contributor.authorSchmid-Grendelmeir, P.
dc.contributor.authorGamkrelidze, A.
dc.contributor.authorGarcia-Aymerich, J.
dc.contributor.authorGomez, M.
dc.contributor.authorGonzález Diaz, S.
dc.contributor.authorGotua, M.
dc.contributor.authorGuldemond, N. A.
dc.contributor.authorGuzmán, M.-A.
dc.contributor.authorHajjam, J.
dc.contributor.authorHourihane, Jonathan O'B.
dc.contributor.authorHumbert, M.
dc.contributor.authorIaccarino, G.
dc.contributor.authorIerodiakonou, D.
dc.contributor.authorIllario, M.
dc.contributor.authorIvancevich, J. C.
dc.contributor.authorJoos, G.
dc.contributor.authorJung, K.-S.
dc.contributor.authorJutel, M.
dc.contributor.authorKaidashev, I.
dc.contributor.authorKalayci, O.
dc.contributor.authorKardas, P.
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dc.contributor.authorKritikos, V.
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dc.contributor.authorMösges, R.
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dc.contributor.authorPanzner, P.
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dc.contributor.authorPépin, J.-L.
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dc.contributor.authorPfaar, O.
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dc.contributor.authorReitsma, S.
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dc.contributor.authorSalimäki, J.
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dc.contributor.authorYorgancioglu, A.
dc.contributor.authorYusuf, O. M.
dc.contributor.authorZar, H. J.
dc.contributor.authorZeng, S.
dc.contributor.authorZernotti, M.
dc.contributor.authorZhang, L.
dc.contributor.authorZhong, N. S.
dc.contributor.authorZidarn, M.
dc.contributor.authorBousquet, J.
dc.contributor.authorHellings, P. W.
dc.contributor.authorAberer, W.
dc.contributor.authorAgache, I.
dc.contributor.authorAkdis, M.
dc.contributor.authorAliberti, M. R.
dc.contributor.authorAlmeida, R.
dc.contributor.authorAmat, F.
dc.contributor.authorAngles, R.
dc.contributor.authorAnnesi-Maesano, I.
dc.contributor.authorAnsotegui, I. J.
dc.contributor.authorAnto, J. M.
dc.contributor.authorArnavielle, S.
dc.contributor.authorAsayag, E.
dc.contributor.authorAsarnoj, A.
dc.contributor.authorArshad, H.
dc.contributor.authorAvolio, F.
dc.contributor.authorBacci, E.
dc.contributor.authorBachert, C.
dc.contributor.authorBaiardini, I.
dc.contributor.authorBarbara, C.
dc.contributor.authorBarbagallo, M.
dc.contributor.authorBaroni, I.
dc.contributor.authorBarreto, B. A.
dc.contributor.authorBasagana, X.
dc.contributor.authorBateman, Eric D.
dc.contributor.authorBedolla-Barajas, M.
dc.contributor.authorBedbrook, A.
dc.contributor.authorBewick, M.
dc.contributor.authorBeghé, B.
dc.contributor.authorBel, E. H.
dc.contributor.authorBergmann, K. C.
dc.contributor.authorBennoor, K. S.
dc.contributor.authorBenson, M.
dc.contributor.authorBertorello, L.
dc.contributor.authorBiałoszewski, A. Z.
dc.contributor.authorBieber, T.
dc.contributor.authorBialek, S.
dc.contributor.authorBindslev-Jensen, C.
dc.contributor.authorBjermer, L.
dc.contributor.authorBlain, H.
dc.contributor.authorBlasi, F.
dc.contributor.authorBlua, A.
dc.contributor.authorBochenska Marciniak, M.
dc.contributor.authorBogus-Buczynska, I.
dc.contributor.authorARIA Study Group, The
dc.contributor.authorMASK Study Group, The
dc.contributor.funderEIT Health
dc.contributor.funderEuropean Forum for Research and Education in Allergy and Airway Diseases
dc.description.abstractBackground: In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizational health literacy. Main body: As an example for chronic disease care, MASK (Mobile Airways Sentinel NetworK), a new project of the ARIA (Allergic Rhinitis and its Impact on Asthma) initiative, and POLLAR (Impact of Air POLLution on Asthma and Rhinitis, EIT Health), in collaboration with professional and patient organizations in the field of allergy and airway diseases, are proposing real-life ICPs centred around the patient with rhinitis, and using mHealth to monitor environmental exposure. Three aspects of care pathways are being developed: (i) Patient participation, health literacy and self-care through technology-assisted “patient activation”, (ii) Implementation of care pathways by pharmacists and (iii) Next-generation guidelines assessing the recommendations of GRADE guidelines in rhinitis and asthma using real-world evidence (RWE) obtained through mobile technology. The EU and global political agendas are of great importance in supporting the digital transformation of health and care, and MASK has been recognized by DG Santé as a Good Practice in the field of digitally-enabled, integrated, person-centred care. Conclusion: In 20 years, ARIA has considerably evolved from the first multimorbidity guideline in respiratory diseases to the digital transformation of health and care with a strong political involvement.en
dc.description.sponsorshipEIT Health (POLLAR); EUFOREA (ARIA)
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.identifier.citationBousquet, J. J. ; Schünemann, H. J. ; Togias, A. ; Erhola, M. ; Hellings, P. W. ; Zuberbier, T. ; Agache, I. ; Ansotegui, I. J. ; Anto, J. M. ; Bachert, C. ; Becker, S. ; Bedolla-Barajas, M. ; Bewick, M. ; Bosnic-Anticevich, S. ; Bosse, I. ; Boulet, L. P. ; Bourrez, J. M. ; Brusselle, G. ; Chavannes, N. ; Costa, E. ; Cruz, A. A. ; Czarlewski, W. ; Fokkens, W. J. ; Fonseca, J. A. ; Gaga, M. ; Haahtela, T. ; Illario, M. ; Klimek, L. ; Kuna, P. ; Kvedariene, V. ; Le, L. T. T. ; Larenas-Linnemann, D. ; Laune, D. ; Lourenço, O. M. ; Menditto, E. ; Mullol, J. ; Okamoto, Y. ; Papadopoulos, N. ; Pham-Thi, N. ; Picard, R. ; Pinnock, H. ; Roche, N. ; Roller-Wirnsberger, R. E. ; Rolland, C. ; Samolinski, B. ; Sheikh, A. ; Toppila-Salmi, S. ; Tsiligianni, I. ; Valiulis, A. ; Valovirta, E. ; Vasankari, T. ; Ventura, M.-T. ; Walker, S. ; Williams, S. ; Akdis, C. A. ; Annesi-Maesano, I. ; Arnavielhe, S. ; Basagana, X. ; Bateman, E. ; Bedbrook, A. ; Bennoor, K. S. ; Benveniste, S. ; Bergmann, K. C. ; Bialek, S. ; Billo, N. ; Bindslev-Jensen, C. ; Bjermer, L. ; Blain, H. ; Bonini, M. ; Bonniaud, P. ; Bouchard, J. ; Briedis, V. ; Brightling, C. E. ; Brozek, J. ; Buhl, R. ; Buonaiuto, R. ; Canonica, G. W. ; Cardona, V. ; Carriazo, A. M. ; Carr, W. ; Cartier, C. ; Casale, T. ; Cecchi, L. ; Cepeda Sarabia, A. M. ; Chkhartishvili, E. ; Chu, D. K. ; Cingi, C. ; Colgan, E. ; de Sousa, J. C. ; Courbis, A. L. ; Custovic, A. ; Cvetkosvki, B. ; D’Amato, G. ; da Silva, J. ; Dantas, C. ; Dokic, D. ; Dauvilliers, Y. ; Dedeu, A. ; De Feo, G. ; Devillier, P. ; Di Capua, S. ; Dykewickz, M. ; Dubakiene, R. ; Ebisawa, M. ; El-Gamal, Y. ; Eller, E. ; Emuzyte, R. ; Farrell, J. ; Fink-Wagner, A. ; Fiocchi, A. ; Fontaine, J. F. ; Gemicioğlu, B. ; Schmid-Grendelmeir, P. ; Gamkrelidze, A. ; Garcia-Aymerich, J. ; Gomez, M. ; González Diaz, S. ; Gotua, M. ; Guldemond, N. A. ; Guzmán, M.-A. ; Hajjam, J. ; Hourihane, Jonathan O'B. ; Humbert, M. ; Iaccarino, G. ; Ierodiakonou, D. ; Illario, M. ; Ivancevich, J. C. ; Joos, G. ; Jung, K.-S. ; Jutel, M. ; Kaidashev, I. ; Kalayci, O. ; Kardas, P. ; Keil, T. ; Khaitov, M. ; Khaltaev, N. ; Kleine-Tebbe, J. ; Kowalski, M. L. ; Kritikos, V. ; Kull, I. ; Leonardini, L. ; Lieberman, P. ; Lipworth, B. ; Lodrup Carlsen, K. C. ; Loureiro, C. C. ; Louis, R. ; Mair, A. ; Marien, G. ; Mahboub, B. ; Malva, J. ; Manning, P. ; De Manuel Keenoy, E. ; Marshall, G. D. ; Masjedi, M. R. ; Maspero, J. F. ; Mathieu-Dupas, E. ; Matricardi, P. M. ; Melén, E. ; Melo-Gomes, E. ; Meltzer, E. O. ; Menditto, E. ; Mercier, J. ; Miculinic, N. ; Mihaltan, F. ; Milenkovic, B. ; Moda, G. ; Mogica-Martinez, M.-D. ; Mohammad, Y. ; Montefort, S. ; Monti, R. ; Morais-Almeida, M. ; Mösges, R. ; Münter, L. ; Muraro, A. ; Murray, R. ; Naclerio, R. ; Napoli, L. ; Namazova-Baranova, L. ; Neffen, H. ; Nekam, K. ; Neou, A. ; Novellino, E. ; Nyembue, D. ; O'Hehir, R. ; Ohta, K. ; Okubo, K. ; Onorato, G. ; Ouedraogo, S. ; Pali-Schöll, I. ; Palkonen, S. ; Panzner, P. ; Park, H.-S. ; Pépin, J.-L. ; Pereira, A.-M. ; Pfaar, O. ; Paulino, E. ; Phillips, J. ; Picard, R. ; Plavec, D. ; Popov, T. A. ; Portejoie, F. ; Price, D. ; Prokopakis, E. P. ; Pugin, B. ; Raciborski, F. ; Rajabian-Söderlund, R. ; Reitsma, S. ; Rodo, X. ; Romano, A. ; Rosario, N. ; Rottem, M. ; Ryan, D. ; Salimäki, J. ; Sanchez-Borges, M. M. ; Sisul, J.-C. ; Solé, D. ; Somekh, D. ; Sooronbaev, T. ; Sova, M. ; Spranger, O. ; Stellato, C. ; Stelmach, R. ; Suppli Ulrik, C. ; Thibaudon, M. ; To, T. ; Todo-Bom, A. ; Tomazic, P. V. ; Valero, A. A. ; Valenta, R. ; Valentin-Rostan, M. ; van der Kleij, R. ; V;enplas, O. ; Vezzani, G. ; Viart, F. ; Viegi, G. ; Wallace, D. ; Wagenmann, M. ; Wang, D. Y. ; Waserman, S. ; Wickman, M. ; Williams, D. M. ; Wong, G. ; Wroczynski, P. ; Yiallouros, P. K. ; Yorgancioglu, A. ; Yusuf, O. M. ; Zar, H. J. ; Zeng, S. ; Zernotti, M. ; Zhang, L. ; Zhong, N. S. ; Zidarn, M. ; Bousquet, J. ; Hellings, P. W. ; Aberer, W. ; Agache, I. ; Akdis, C. A. ; Akdis, M. ; Aliberti, M. R. ; Almeida, R. ; Amat, F. ; Angles, R. ; Annesi-Maesano, I. ; Ansotegui, I. J. ; Anto, J. M. ; Arnavielle, S. ; Asayag, E. ; Asarnoj, A. ; Arshad, H. ; Avolio, F. ; Bacci, E. ; Bachert, C. ; Baiardini, I. ; Barbara, C. ; Barbagallo, M. ; Baroni, I. ; Barreto, B. A. ; Basagana, X. ; Bateman, E. D. ; Bedolla-Barajas, M. ; Bedbrook, A. ; Bewick, M. ; Beghé, B. ; Bel, E. H. ; Bergmann, K. C. ; Bennoor, K. S. ; Benson, M. ; Bertorello, L. ; Białoszewski, A. Z. ; Bieber, T. ; Bialek, S. ; Bindslev-Jensen, C. ; Bjermer, L. ; Blain, H. ; Blasi, F. ; Blua, A. ; Bochenska Marciniak, M. ; Bogus-Buczynska, I. ; ARIA Study Group, The and MASK Study Group, The. (2019) 'Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases', Clinical and Translational Allergy, 9, 44 (15 pp.). DOI:10.1186/s13601-019-0279-2en
dc.identifier.journaltitleClinical and Translational Allergyen
dc.publisherBMC (part of Springer Nature)en
dc.rights© The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.en
dc.subjectHealth care transformationen
dc.subjectCare pathwaysen
dc.titleNext-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseasesen
dc.typeArticle (peer-reviewed)en
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