Darned in 2013: inclusion of model organisms and linking with Wikipedia

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dc.contributor.authorKiran, Anmol M.
dc.contributor.authorO'Mahony, John J.
dc.contributor.authorSanjeev, Komal
dc.contributor.authorBaranov, Pavel V.
dc.contributor.funderWellcome Trust
dc.contributor.funderScience Foundation Ireland
dc.date.accessioned2017-11-14T13:24:30Z
dc.date.available2017-11-14T13:24:30Z
dc.date.issued2013
dc.description.abstractDARNED (DAtabase of RNA EDiting, available at http://darned.ucc.ie) is a centralized repository of reference genome coordinates corresponding to RNA nucleotides having altered templated identities in the process of RNA editing. The data in DARNED are derived from published datasets of RNA editing events. RNA editing instances have been identified with various methods, such as bioinformatics screenings, deep sequencing and/or biochemical techniques. Here we report our current progress in the development and expansion of the DARNED. In addition to novel database features the DARNED update describes inclusion of Drosophila melanogaster and Mus musculus RNA editing events and the launch of a community-based annotation in the RNA WikiProject.en
dc.description.sponsorshipScience Foundation Ireland (06/IN.1/B81); Wellcome Trust (094423)en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationKiran, A. M., O'Mahony, J. J., Sanjeev, K. and Baranov, P. V. (2013) 'Darned in 2013: inclusion of model organisms and linking with Wikipedia', Nucleic Acids Research, 41(D1), pp. 258-261. doi: 10.1093/nar/gks961en
dc.identifier.doi10.1093/nar/gks961
dc.identifier.endpage261
dc.identifier.issn0305-1048
dc.identifier.issuedD1
dc.identifier.journaltitleNucleic Acids Researchen
dc.identifier.startpage258
dc.identifier.urihttps://hdl.handle.net/10468/5021
dc.identifier.volume41
dc.language.isoenen
dc.publisherOxford University Pressen
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Principal Investigator Programme (PI)/06/IN.1/B81/IE/RNA editing in humans: Identification prediction and therapeutic application/
dc.relation.urihttps://academic.oup.com/nar/article/41/D1/D258/1074741/Darned-in-2013-inclusion-of-model-organisms-and
dc.rights© 2012, the Authors. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.en
dc.rights.urihttps://creativecommons.org/licenses/by-nc/3.0/
dc.subjectDNA-sequence differencesen
dc.subjectRNA editing sitesen
dc.subjectTo-inosine RNAen
dc.subjectHuman transcriptomeen
dc.subjectWidespread RNAen
dc.subjectAccurate identificationen
dc.subjectADAR deaminasesen
dc.subjectMessenger RNAen
dc.subjectParallel DNAen
dc.subjectDatabaseen
dc.titleDarned in 2013: inclusion of model organisms and linking with Wikipediaen
dc.typeArticle (peer-reviewed)en
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