A scoping review of factors affecting COVID-19 vaccination uptake and deployment in global healthcare systems

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dc.contributor.authorKandulu, Chikondi C.en
dc.contributor.authorSahm, Laura J.en
dc.contributor.authorSaab, Mohamad M.en
dc.contributor.authorO'Driscoll, Michelleen
dc.contributor.authorMcCarthy, Meganen
dc.contributor.authorShorter, Gillian W.en
dc.contributor.authorBerry, Emmaen
dc.contributor.authorMoore, Anne C.en
dc.contributor.authorFleming, Aoifeen
dc.contributor.funderHigher Education Authorityen
dc.date.accessioned2024-09-25T11:30:20Z
dc.date.available2024-09-25T11:30:20Z
dc.date.issued2024-09-25en
dc.description.abstractIntroduction: COVID-19 vaccines were rapidly developed and deployed on a large scale during a global crisis. A range of deployment strategies were used globally to maximize vaccine uptake. In this scoping review, we identify and analyze the main healthcare system and policy factors that guided and influenced COVID-19 vaccination deployment and uptake globally. Materials and Methods: JBI guidelines, Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR), and the population, concept, and context (PCC) framework were applied. Studies on individual COVID-19 vaccination factors, such as vaccine hesitancy, were excluded. The search was last conducted in May 2024 yielding 26,686 articles from PubMed, Embase, CINAHL, Scopus, and COVID-19 websites. A total of 47 articles and 3 guidance documents were included. The results of the thematic analysis were mapped to the Consolidated Framework for Implementation Research (CFIR). Results: The results found the following healthcare system and policy factors as integral to COVID-19 vaccination: types of vaccine products, healthcare workforce capacity, procurement strategies, distribution and cold-chain capacity, partnership, coordination, and leadership, information, communication, and registration strategies, delivery models, organizations, the existing health systems and policies on prioritization of at-risk groups and deployment plans. Discussion: Globally, COVID-19 vaccination programs responded to the pandemic by leveraging and reforming the existing healthcare systems, relying on strong leadership and global cooperation (such as the COVID-19 Vaccines Global Access Initiative). Deployment was enabled by effective communication and adoption of innovative technologies using data-driven policies to create high vaccine demand while overcoming limited vaccine supply and rapidly adapting to uncertainties.en
dc.description.sponsorshipHigher Education Authority (North-South Research Programme: All-island Vaccine Research and Training Alliance (AIVRT))en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleid1093en
dc.identifier.citationKandulu, C. C., Sahm, L. J., Saab, M. M., O'Driscoll, M., McCarthy, M., Shorter, G. W., Berry, E., Moore, A. C. and Fleming, A. (2024) 'A scoping review of factors affecting COVID-19 vaccination uptake and deployment in global healthcare systems', Vaccines,12(10), 1093 (20pp). https://doi.org/10.3390/vaccines12101093en
dc.identifier.doi10.3390/vaccines12101093en
dc.identifier.endpage20en
dc.identifier.issn2076-393Xen
dc.identifier.issued10en
dc.identifier.journaltitleVaccinesen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/16447
dc.identifier.volume12en
dc.language.isoenen
dc.publisherMDPIen
dc.rights© 2024, the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectCOVID-19 vaccinesen
dc.subjectHealthcare systemsen
dc.subjectVaccination strategiesen
dc.subjectVaccine rollouten
dc.subjectVaccine implementationen
dc.subjectVaccine accessen
dc.subjectVaccine deploymenten
dc.subjectVaccine campaignen
dc.subjectImmunization programsen
dc.subjectHealth policyen
dc.subject~Pharmacy - Journal Articles~en
dc.titleA scoping review of factors affecting COVID-19 vaccination uptake and deployment in global healthcare systemsen
dc.typeArticle (peer-reviewed)en
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