Bacterial toxins: Offensive, defensive, or something else altogether?

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dc.contributor.authorRudkin, Justine K.
dc.contributor.authorMcLoughlin, Rachel M.
dc.contributor.authorPreston, Andrew
dc.contributor.authorMassey, Ruth C.
dc.date.accessioned2022-09-15T13:43:31Z
dc.date.available2022-09-15T13:43:31Z
dc.date.issued2017-09-21
dc.date.updated2022-09-15T13:36:58Z
dc.description.abstractThe secretion of proteins that damage host tissue is well established as integral to the infectious processes of many bacterial pathogens. However, recent advances in our understanding of the activity of toxins suggest that the attributes we have assigned to them from early in vitro experimentation have misled us into thinking of them as merely destructive tools. Here, we will discuss the multifarious ways in which toxins contribute to the lifestyle of bacteria and, by considering their activity from an evolutionary perspective, demonstrate how this extends far beyond their ability to destroy host tissue.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleide1006452en
dc.identifier.citationRudkin, J. K., McLoughlin, R. M., Preston, A. and Massey, R. C. (2017) 'Bacterial toxins: Offensive, defensive, or something else altogether?', PLOS Pathogens, 13(9), e1006452 (12pp). doi: 10.1371/journal.ppat.1006452en
dc.identifier.doi10.1371/journal.ppat.1006452en
dc.identifier.eissn1553-7374
dc.identifier.endpage12en
dc.identifier.issn1553-7366
dc.identifier.issued9en
dc.identifier.journaltitlePLOS Pathogensen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/13610
dc.identifier.volume13en
dc.language.isoenen
dc.publisherPublic Library of Scienceen
dc.rights© 2017 Rudkin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectBacteriaen
dc.subjectToxinen
dc.titleBacterial toxins: Offensive, defensive, or something else altogether?en
dc.typeArticle (peer-reviewed)en
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