Evaluating measures of allostatic load in adolescents: A systematic review

dc.contributor.authorWhelan, Eadaoinen
dc.contributor.authorO’Shea, Jenen
dc.contributor.authorHunt, Eithneen
dc.contributor.authorDockray, Samanthaen
dc.date.accessioned2023-03-31T13:26:39Z
dc.date.available2023-03-31T13:26:39Z
dc.date.issued2021-06-29en
dc.description.abstractBackground: Adolescents can experience heightened stress due to biopsychosocial changes that occur during this developmental stage. The ‘wear and tear’ of the physiological systems responsible for managing our stress response can lead to dysregulation of these systems, known as allostatic load (AL). AL is commonly measured within adult populations, however, inconsistencies exist across measures used to quantify the effects of stress on health. The aim of this review was to identify variations in measures across AL studies, and to consider how specific measures may be more appropriate for use within adolescent populations. Method: Pubmed, PsycINFO, PsycARTICLES, Academic Search Complete, were searched in July 2020, using search terms ‘allostatic load’ and ‘adolescence’. AL studies (1988–2020) with an adolescent population (age 10–24 years) were included. 354 records were screened by two reviewers and 41 full-text articles were assessed for eligibility. Results: 25 studies were included in final synthesis. Biomarkers of AL ranged from 1 to 14. The most common index of AL consisted of 6 biomarkers; cortisol, epinephrine, norepinephrine, systolic blood pressure, diastolic blood pressure, and body-mass index. Findings: Defining measures of AL during adolescence may help to identify vulnerabilities specific to adolescents, which may shape their lifelong health trajectories.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleid105324en
dc.identifier.citationWhelan, E., O’Shea, J., Hunt, E. and Dockray, S. (2021) 'Evaluating measures of allostatic load in adolescents: A systematic review', Psychoneuroendocrinology, 131, 105324 (9pp). doi: 10.1016/j.psyneuen.2021.105324en
dc.identifier.doi10.1016/j.psyneuen.2021.105324en
dc.identifier.endpage9en
dc.identifier.issn0306-4530en
dc.identifier.journaltitlePsychoneuroendocrinologyen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/14347
dc.identifier.volume131en
dc.language.isoenen
dc.publisherElsevier B.V.en
dc.rights© 2021, the Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectAllostatic loaden
dc.subjectAdolescentsen
dc.subjectStressen
dc.subjectAllostasisen
dc.subjectAdolescenceen
dc.titleEvaluating measures of allostatic load in adolescents: A systematic reviewen
dc.typeArticle (peer-reviewed)en
oaire.citation.volume131en
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