Validity of the Japanese version of the quick mild cognitive impairment screen

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dc.contributor.authorMorita, Ayako
dc.contributor.authorO'Caoimh, Rónán
dc.contributor.authorMurayama, Hiroshi
dc.contributor.authorMolloy, D. William
dc.contributor.authorInoue, Shigeru
dc.contributor.authorShobugawa, Yugo
dc.contributor.authorFujiwara, Takeo
dc.contributor.funderPfizer Health Research Foundationen
dc.contributor.funderUehara Memorial Foundationen
dc.contributor.funderTokyo Medical and Dental Universityen
dc.date.accessioned2019-11-19T10:12:37Z
dc.date.available2019-11-19T10:12:37Z
dc.date.issued2019-03-14
dc.description.abstractEarly detection of dementia provides opportunities for interventions that could delay or prevent its progression. We developed the Japanese version of the Quick Mild Cognitive Impairment (Qmci-J) screen, which is a performance-based, easy-to-use, valid and reliable short cognitive screening instrument, and then we examined its validity. Community-dwelling adults aged 65–84 in Niigata prefecture, Japan, were concurrently administered the Qmci-J and the Japanese version of the standardized Mini-Mental State Examination (sMMSE-J). Mild cognitive impairment (MCI) and dementia were categorized using established and age-adjusted sMMSE-J cut-offs. The sample (n = 526) included 52 (9.9%) participants with suspected dementia, 123 (23.4%) with suspected MCI and 351 with likely normal cognition. The Qmci-J showed moderate positive correlation with the sMMSE-J (r = 0.49, p < 0.001) and moderate discrimination for predicting suspected cognitive impairment (MCI/dementia) based on sMMSE-J cut-offs, area under curve: 0.74, (95%CI: 0.70–0.79), improving to 0.76 (95%CI: 0.72 to 0.81) after adjusting for age. At a cut-off of 60/61/100, the Qmci-J had a 73% sensitivity, 68% specificity, 53% positive predictive value, and 83% negative predictive value for cognitive impairment. Normative data are presented, excluding those with any sMMSE-J < 27. Though further research is required, the Qmci-J screen may be a useful screening tool to identify older adults at risk of cognitive impairment.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleid917en
dc.identifier.citationMorita, A., O’Caoimh, R., Murayama, H., Molloy, D.W., Inoue, S., Shobugawa, Y. and Fujiwara, T., 2019. Validity of the Japanese Version of the Quick Mild Cognitive Impairment Screen. International journal of environmental research and public health, 16(6), (917). DOI:10.3390/ijerph16060917en
dc.identifier.doi10.3390/ijerph16060917en
dc.identifier.eissn1660-4601
dc.identifier.endpage10en
dc.identifier.issn1661-7827
dc.identifier.issued6en
dc.identifier.journaltitleInternational Journal of Environmental Research and Public Healthen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/9043
dc.identifier.volume16en
dc.language.isoenen
dc.publisherMDPIen
dc.relation.urihttps://www.mdpi.com/1660-4601/16/6/917
dc.rights© 2019 by the authors. Licensee MDPI, Basel, Switzerlanden
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectCognitive impairmenten
dc.subjectShort cognitive screen instrumenten
dc.subjectJapaneseen
dc.subjectOlder adultsen
dc.subjectScreeningen
dc.titleValidity of the Japanese version of the quick mild cognitive impairment screenen
dc.typeArticle (peer-reviewed)en
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