Colorectal cancer detection based on the extraction of scattering properties and biochemical concentrations from fluorescence spectroscopy measurements

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Date
2022-04
Authors
Nogueira, Marcelo S.
Matthews, Robert
Killeen, Shane
Oâ Riordain, Micheal
Andersson-Engels, Stefan
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Optica Publishing Group
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Abstract
We report the first study estimating fluorophore and chromophore concentrations with scattering properties for colorectal cancer detection, as well as one of the first studies performing such estimation based on fluorescence spectra alone.
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Keywords
Colorectal cancer (CRC) , Colorectal cancer detection , Fluorescence spectra , Absorption coefficient , Diffuse reflectance spectroscopy , Fluorescence spectroscopy , Light propagation , Mie theory , Rayleigh scattering
Citation
Nogueira, M.S., Matthews, R., Killeen, S., O’Riordain, M. and Andersson-Engels, S. (2022) ‘Colorectal cancer detection based on the extraction of scattering properties and biochemical concentrations from fluorescence spectroscopy measurements’, in Biophotonics Congress: Biomedical Optics 2022 (Translational, Microscopy, OCT, OTS, BRAIN). Fort Lauderdale, Florida, 24-27 April, Optica Publishing Group, TS2B.5, (2 pp). https://doi.org/10.1364/TRANSLATIONAL.2022.TS2B.5.
Copyright
© 2022 The Author(s). Published by Optical Publishing Group