Recode-2: new design, new search tools, and many more genes

Simple item page
dc.contributor.authorBekaert, Michael
dc.contributor.authorFirth, Andrew E.
dc.contributor.authorZhang, Yan
dc.contributor.authorGladyshev, Vadim N.
dc.contributor.authorAtkins, John F.
dc.contributor.authorBaranov, Pavel V.
dc.contributor.funderScience Foundation Ireland
dc.contributor.funderNational Institutes of Health
dc.date.accessioned2017-11-14T13:24:32Z
dc.date.available2017-11-14T13:24:32Z
dc.date.issued2010
dc.description.abstractRecoding' is a term used to describe non-standard read-out of the genetic code, and encompasses such phenomena as programmed ribosomal frame-shifting, stop codon readthrough, selenocysteine insertion and translational bypassing. Although only a small proportion of genes utilize recoding in protein synthesis, accurate annotation of 'recoded' genes lags far behind annotation of 'standard' genes. In order to address this issue, provide a service to researchers in the field, and offer training data for developers of gene-annotation software, we have gathered together known cases of recoding within the Recode database. Recode-2 is an improved and updated version of the database. It provides access to detailed information on genes known to utilize translational recoding and allows complex search queries, browsing of recoding data and enhanced visualization of annotated sequence elements. At present, the Recode-2 database stores information on approximately 1500 genes that are known to utilize recoding in their expression-a factor of approximately three increase over the previous version of the database. Recode-2 is available at http://recode.ucc.ieen
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationBekaert, M., Firth, A. E., Zhang, Y., Gladyshev, V. N., Atkins, J. F. and Baranov, P. V. (2010) 'Recode-2: new design, new search tools, and many more genes', Nucleic Acids Research, 38(D1), pp. 69-74. doi: 10.1093/nar/gkp788en
dc.identifier.doi10.1093/nar/gkp788
dc.identifier.endpage74
dc.identifier.issn0305-1048
dc.identifier.issuedD1
dc.identifier.journaltitleNucleic Acids Researchen
dc.identifier.startpage69
dc.identifier.urihttps://hdl.handle.net/10468/5029
dc.identifier.volume38
dc.language.isoenen
dc.publisherOxford University Pressen
dc.relation.urihttps://academic.oup.com/nar/article-lookup/doi/10.1093/nar/gkp788
dc.rights© 2009, the Authors. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/2.0/uk/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.en
dc.rights.urihttp://creativecommons.org/licenses/by-nc/2.0/uk/
dc.subjectOrnithine decarboxylase antizymeen
dc.subjectPolymerase III holoenzymeen
dc.subjectRelease factor 2en
dc.subjectSite transfer RNAen
dc.subjectEscherichia-colien
dc.subjectGamma subuniten
dc.subjectTranscriptional slippageen
dc.subjectSelenoprotein synthesisen
dc.subjectMessenger RNAsen
dc.subjectCoding gapen
dc.titleRecode-2: new design, new search tools, and many more genesen
dc.typeArticle (peer-reviewed)en
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
3915.pdf
Size:
1.41 MB
Format:
Adobe Portable Document Format
Description:
Published Version
Download
Collections
Biochemistry and Cell Biology - Journal Articles