The economic impact of neovascular age-related macular degeneration (AMD), diabetic retinopathy (DR) and diabetic macular edema (DME): a systematic literature review of the emerging literature

dc.contributor.authorWillmington, Claireen
dc.contributor.authorMurphy, Aileenen
dc.contributor.authorKirby, Annen
dc.contributor.funderEuropean Commissionen
dc.date.accessioned2025-02-25T12:22:12Z
dc.date.available2025-02-25T12:22:12Z
dc.date.issued2024en
dc.description.abstractNeovascular age-related macular degeneration (nAMD), diabetic retinopathy (DR), as well as its consequence, such as diabetic macular edema (DME), are some of the leading causes of vision impairment in people aged 50 years and older. In the advanced stages of these conditions, treatment often relies on repeated intravitreal injections of anti-vascular endothelial growth factors (VEGFs), namely, ranibizumab, aflibercept faricimab, brolucizumab, and bevacizumab (off-label use). While the advent of VEGF injections changed the treatment landscape, Clinical trials investigating the therapeutic potential of gene therapy in nAMD, DR and DME show promising results and may inform future care provision. Given the high price of innovative medicines, it is essential to consider the economic costs associated with these conditions to inform resource allocation decisions.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationWillmington, C., Murphy, A. and Kirby, A. (2024) 'The economic impact of neovascular age-related macular degeneration (AMD), diabetic retinopathy (DR) and diabetic macular edema (DME): a systematic literature review of the emerging literature', ISPOR, Barcelona, Spain, 19th November.en
dc.identifier.urihttps://hdl.handle.net/10468/17114
dc.language.isoenen
dc.rights© 2024, the Authors.en
dc.subjectNeovascular age-related macular degeneration (AMD)en
dc.subjectDiabetic retinopathy (DR)en
dc.subjectDiabetic macular edema (DME)en
dc.titleThe economic impact of neovascular age-related macular degeneration (AMD), diabetic retinopathy (DR) and diabetic macular edema (DME): a systematic literature review of the emerging literatureen
dc.typeConference itemen
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