Application of mathematical modelling for investigating oxygen transfer energy requirement and process design of an aerobic continuous stirred tank fermenter

dc.check.date2019-02-27
dc.check.infoAccess to this article is restricted until 24 months after publication by request of the publisher.en
dc.contributor.authorFitzpatrick, John J.
dc.contributor.authorGonçalves de Lima, Karina
dc.contributor.authorKeller, Eoin
dc.date.accessioned2017-08-21T12:20:25Z
dc.date.available2017-08-21T12:20:25Z
dc.date.issued2017-02-27
dc.date.updated2017-08-21T12:12:46Z
dc.description.abstractFermentation kinetic and oxygen transfer modelling coupled with energy analysis was applied to investigate how key input design variables influenced fermenter size, feed substrate requirement, wasted substrate and aeration system electrical energy requirement. The study showed that trade-offs and compromises are required to select the values of key input variables that can produce superior process designs in terms of the output variables. For example, reducing steady-state oxygen concentration reduced aeration system energy requirements and associated carbon footprint but increased fermenter size and associated cost. Mathematical modelling can assist in more precisely zoning in quantitatively on the selection of design input variable values that can produce a best compromise between conflicting design output variables. Mathematical modelling can also highlight design sensitivities. For example, if the steady-state sugar concentration is reduced below a certain value, then this can lead to an exponential increase in fermenter volume and associated cost, thus it is prudent to operate on the conservative side of this value.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationFitzpatrick, J. J., Gonçalves de Lima, K. and Keller, E. (2017) ‘Application of mathematical modelling for investigating oxygen transfer energy requirement and process design of an aerobic continuous stirred tank fermenter’, Food and Bioproducts Processing, 103, pp. 39-48. doi:10.1016/j.fbp.2017.02.009en
dc.identifier.doi10.1016/j.fbp.2017.02.009
dc.identifier.endpage48en
dc.identifier.issn0960-3085
dc.identifier.journaltitleFood and Bioproducts Processingen
dc.identifier.startpage39en
dc.identifier.urihttps://hdl.handle.net/10468/4472
dc.identifier.volume103en
dc.language.isoenen
dc.publisherElsevier Ltden
dc.rights© 2017, Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license.en
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectContinuous stirred tank fermenteren
dc.subjectProcess designen
dc.subjectMathematical modellingen
dc.subjectEnergyen
dc.subjectEnvironmental impacten
dc.subjectOxygen transferen
dc.titleApplication of mathematical modelling for investigating oxygen transfer energy requirement and process design of an aerobic continuous stirred tank fermenteren
dc.typeArticle (peer-reviewed)en
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