Lutein and zeaxanthin: The possible contribution, mechanisms of action and implications of modern dietary intake for cognitive development in children. [version 1; peer review: 2 approved]

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dc.contributor.authorLoskutova, Ekaterina
dc.contributor.authorShah, Kajal
dc.contributor.authorFlitcroft, Ian D.
dc.contributor.authorSetti, Annalisa
dc.contributor.authorButler, John S.
dc.contributor.authorNolan, Yvonne
dc.contributor.authorPaudel, Nabine
dc.contributor.authorLoughman, James
dc.contributor.funderTechnological University Dublinen
dc.date.accessioned2019-11-26T05:56:01Z
dc.date.available2019-11-26T05:56:01Z
dc.date.issued2019-04-26
dc.description.abstractBackground: Studies suggest that lutein and zeaxanthin may be important for cognitive development in children, but a comprehensive evidence synthesis is lacking. The purpose of this evidence synthesis was to analyse the available data regarding the role of lutein and zeaxanthin for cognition in children and propose a theoretical basis for future studies. Methods: The PubMed, Scopus, the ISRCTN registry and Cochrane Library databases were searched for studies that evaluated the relationship between lutein and zeaxanthin and cognitive function in children. Reference list and ancestry searches were performed on relevant articles. A total of 543 articles were identified, of which six cross-sectional studies were included. Results: The literature search revealed that the evidence concerning the effect of lutein and zeaxanthin on cognition in children is sparse. However, there is some preliminary evidence indicating a positive association between lutein and zeaxanthin and cognition in childhood. Conclusions: The cross-sectional nature of the few studies available and the lack of RCT data indicates a need for further investigation before any firm conclusions can be drawn.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationLoskutova, E., Shah, K., Flitcroft, I.D., Setti, A., Butler, J.S., Nolan, Y., Paudel, N. and Loughman, J., 2019. Lutein and zeaxanthin: The possible contribution, mechanisms of action and implications of modern dietary intake for cognitive development in children. HRB Open Research, 2. (17pp). DOI:10.12688/hrbopenres.12903.1en
dc.identifier.doi10.12688/hrbopenres.12903.1en
dc.identifier.eissn2515-4826
dc.identifier.endpage17en
dc.identifier.issued8en
dc.identifier.journaltitleHRB Open Researchen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/9230
dc.identifier.volume2en
dc.language.isoenen
dc.publisherHealth Research Boarden
dc.relation.urihttps://hrbopenresearch.org/articles/2-8/v1
dc.rights© 2019 Loskutova E et alen
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectLuteinen
dc.subjectZeaxanthinen
dc.subjectDieten
dc.subjectCognitionen
dc.subjectCognitive developmenten
dc.subjectVisionen
dc.subjectChildrenen
dc.titleLutein and zeaxanthin: The possible contribution, mechanisms of action and implications of modern dietary intake for cognitive development in children. [version 1; peer review: 2 approved]en
dc.typeArticle (peer-reviewed)en
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